Video-assisted Thoracic Surgery (VATS)

6

Review clinical trials related to Video-assisted Thoracic Surgery (VATS). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Effects of Intraoperative Heat and Moisture Exchange Systems During Thoracic Surgery: A Prospective Observational Cohort Study

General anesthesia with endotracheal intubation bypasses the physiological warming and humidification functions of the upper airway, allowing cold and dry gases to reach the lower respiratory tract. This may impair mucociliary clearance, increase secretion viscosity, promote atelectasis, and contribute to postoperative pulmonary complications (PPCs). Patients undergoing thoracic surgery, particularly those requiring one-lung ventilation (OLV), are at increased risk for PPCs because of altered ventilation-perfusion matching, reduced functional residual capacity, and impaired secretion clearance. Although respiratory gas humidification is routinely used during anesthesia, evidence regarding the comparative clinical effects of active heated humidification (AHH) and passive heat and moisture exchangers (HMEs) during thoracic surgery remains limited. This prospective observational cohort study aims to evaluate the association between intraoperative respiratory gas humidification methods and postoperative pulmonary complications and perioperative clinical outcomes in adult patients undergoing elective video-assisted thoracoscopic surgery (VATS).

Participants needed: 200
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Marmara UniversityUpdated: Jul 27, 2026Locations: 1Duration: 7 Days
Eligibility criteria

Patients aged 18 to 75 years [+4]

Emergency surgery [+4]

Status: Not yet recruiting

Comparison of Serratus Posterior Superior Intercostal Plane Block and Deep Serratus Anterior Plane Block After Video-Assisted Thoracoscopic Surgery

This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Deep Serratus Anterior Plane Block in patients undergoing Video-Assisted Thoracoscopic Surgery. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, Quality of recovery assessed using the QoR-15 questionnaire.

Participants needed: 60
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Antalya City HospitalUpdated: May 11, 2026Locations: 1
Eligibility criteria

Patients aged 18-65 years [+5]

Refusal to participate [+8]

Status: Not yet recruiting

Effect of Early Versus Late Surgical Intercostal Block on Postoperative Pain Relief Following Video-Assisted Thoracic Surgery (VATS)

Video-assisted thoracoscopic surgery (VATS) is associated with significant postoperative pain despite lower morbidity compared with thoracotomy. Adequate pain management is essential within Enhanced Recovery After Surgery (ERAS) pathways to preserve respiratory function and facilitate postoperative recovery. Surgical intercostal block performed under direct vision is a simple and effective regional analgesic technique commonly used following VATS. However, the optimal timing of intercostal block administration during surgery remains uncertain. This prospective randomized double-blind study will compare surgical intercostal block performed at the beginning versus the end of the surgical procedure. The study aims to evaluate the effect of block timing on postoperative pain intensity and postoperative opioid consumption. The results may help optimize multimodal analgesic strategies in patients undergoing thoracic surgery.

Participants needed: 140
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Erasme University HospitalUpdated: Apr 16, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years [+3]

Neurological or psychiatric conditions that compromise the reliable assessment o... [+10]

Status: Recruiting

High Dose Dexamethasone to Reduce Postoperative Pain After Video-Assisted Thoracoscopic Surgery Lobectomy /Segmentectomy

The aim is to conduct a randomized controlled trial (RCT) with a high dose arm (1mg/kg) vs a low dose (8mg in total) of steroid (Dexamethasone) given intravenous (IV) after the induction of anesthesia to "High-pain-responders" in patients undergoing VATS lobectomy/segmentectomy. The hypothesis is that a high dose of Dexamethasone can lower pain when coughing in the morning after VATS lobectomy/segmentectomy, in patients scoring as "High-pain-responders" on the Pain-Catastrophizing-Scale

Participants needed: 80
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Rigshospitalet, DenmarkUpdated: Jan 7, 2026Locations: 1
Eligibility criteria

Age ≥ 18 year [+4]

Patients undergoing systemic glucocorticoid or other immunosuppressive therapies... [+9]

Status: Recruiting

Erector Spinae Plane Block Versus Serratus Anterior Plane Block in VATS

Pain control remains challenging in patients undergoing video-assisted thoracoscopic surgery (VATS). It is advised to use a regional block to lower postoperative opioid usage. This study evaluates efficacy of Erector spinae plane (ESP) block in comparison to Serratus anterior plane block (SAP) in pain management for patients undergoing video-assisted thoracoscopic surgery(VATS).

Participants needed: 40
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: May 30, 2025Locations: 1
Eligibility criteria

body mass index (BMI)=18 to 40 kg/m2

Contraindications to regional anesthesia as bleeding disorders , allergy to loca... [+3]

Status: Not yet recruiting

Effectiveness of Respiratory Muscle Training with a Mobile Application After Lobectomy

It has been observed that there are negative effects on respiratory muscle strength following lobectomy. This has led to the necessity of respiratory muscle training to mitigate these adverse effects. Most studies conducted so far focus on the late postoperative period, and there are only a few studies evaluating the effectiveness of early postoperative inspiratory muscle training (IMT). It is believed that this method could be useful for facilitating patient follow-up and increasing patient motivation through visual feedback.

Participants needed: 45
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Hacettepe UniversityUpdated: Feb 6, 2025Locations: 1
Eligibility criteria

Volunteering to participate in the study, [+4]

Having any orthopedic or neurological problem that prevents walking, [+2]