Clinical trials

10

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Assessment of Cervical Range of Motion Restrictions in Infants With Arthrogenic Torticollis - A Feasibility Study

Babies with torticollis (a tilted or twisted neck) have difficulty turning their head fully to the side. Small movement sensors = Inertial Measurement Units (IMUs) can be used to measure how far they can turn their head. In an earlier study, these measurements were carried out by a trained professional. We now want to find out whether parents can do the measurements themselves at home and whether this works well in everyday practice.

Participants needed: 10
Trial details
Age: 3-8Biological sex: AllType: ObservationalSponsor: Balgrist University HospitalUpdated: Oct 8, 2026
Eligibility criteria

Age between 3 and 8 months at the time of the measurements [+2]

Previous surgery or injury to the cervical spine [+4]

Status: Not yet recruiting

Markerless Motion Capture in Foot and Ankle Surgery

Proof of Concept: ROM measured by the markerless system compared to clinical examination using a goniometer and motion capture analysis. The ROM of the ankle joint in the sagittal plane and the ROM of the subtalar joint in coronal plane of 20 healthy subjects will be analysed using three different methods: Clinical examination using a goniometer, Markerbased motion capture system, Markerless movement analysis. ROM measurements will be performed on both feet of 20 participants (40 feet total). Each measurement method will be performed 10 times per foot. Goniometer measurements will be performed by two independent investigators (10 measurements each), while marker-based and marker-less measure

Participants needed: 20
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Balgrist University HospitalUpdated: Sep 30, 2026Duration: 1 Day
Eligibility criteria

Healthy subjects between 18 - 65 years of age able to sign the informed consent...

Injury, diseases or former surgery affecting the lower limb. Stiff joint, e.g. b...

Status: Recruiting

Vertebropexy - Randomized-controlled Trial

To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)

Participants needed: 164
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Balgrist University HospitalUpdated: Sep 28, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years [+4]

Indication for decompression and/or fusion surgery in patients with solely disc... [+6]

Status: Recruiting

Foot/Extremities at 7T MRI

* To evaluate standard clinical sequences for 7 Tesla MRI of the foot and extremities to improve detailed depiction of the complex anatomy of this region. * To evaluate various pathologies of the foot and extremities (plantar plate tears, Morton neuroma, tendon tears, ligament tears etc.).

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Balgrist University HospitalUpdated: Jul 16, 2026Locations: 1Duration: 3 Years
Eligibility criteria

Informed consent as documented by signature (Appendix Informed Consent Form) [+3]

previous foot/ extremities surgery with metal in vivo [+2]

Status: Recruiting

Monitored Effects of Physical Activity on Fetal Heart Rate by Using a Wireless Non-invasive Device

Effect of acute exercise testing in pregnant athletes on maternal and fetal heart rate, fetal/maternal bloodflow and cardiotocogramm assessment.

Participants needed: 20
Trial details
Age: 18-45Biological sex: FemaleType: ObservationalSponsor: Balgrist University HospitalUpdated: Jul 9, 2026Locations: 2
Eligibility criteria

Presence of signed informed consent form [+3]

No signed informed consent form or revocation of consent [+1]

Status: Recruiting

7 Tesla MRI Evaluation of the Spine (Asymptomatic)

High-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots/ganglia. Secondly, detailed anatomy of vertebral artery and its relation to neural structures / foramina can be assessed.

Participants needed: 600
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Balgrist University HospitalUpdated: Jul 8, 2026Locations: 1
Eligibility criteria

Informed consent as documented by signature (Appendix Informed Consent Form) [+2]

previous surgery [+4]

Status: Not yet recruiting

3T Magnetic Resonance Neurography

The goal of this observational study is to evaluate whether optimized high-resolution MRI can better visualize very fine nerves in the cervical spine and neck region compared to standard MRI. The main question it aims to answer is: Can high-resolution MRI reliably show small nerves and potentially detect their injuries or diseases that are often invisible on conventional MRI scans? Participants will come once to Balgrist University Hospital for a one-hour visit. They will fill out a questionnaire and have a single 30-minute MRI scan of the cervical spine without contrast.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Balgrist University HospitalUpdated: Apr 7, 2026Locations: 1
Eligibility criteria

<18 years of age [+3]

Status: Recruiting

Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery

The perioperative antibiotic prophylaxis is evidence-based in orthopedic surgery. While its duration ranges from a single dose to three doses throughout the world, the choice of the prophylactic agents is undisputed. Worldwide, the surgeons use 1st or 2nd-generation cephalosporins (or vancomycin in some cases). However, there are particular clinical situation with a high risk of antibiotic-resistant surgical site infections (SSI); independently of the duration of adminis-tered prophylaxis. These resistant SSI's occur in contaminated wounds, or during surgery under current therapeutic antibiotics, and base on "selection" by antibiotics used for therapy or for prophylaxis.

Participants needed: 1,100
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Balgrist University HospitalUpdated: Dec 2, 2024Locations: 1
Eligibility criteria

Age ≥ 18 years [+6]

Inability to understand the study procedure for linguistic or cognitive rea-sons [+5]

Status: Not yet recruiting

Augmented Reality in Learning Anatomy: The TEACHANATOMY Randomized Cross-over Trial

Cadaver use in anatomy education is undergoing several limitations in many universities, due to high costs, time constraints and supply difficulties. As alternatives to cadaver dissections, new teaching methods based on visual technologies, such as augmented reality (AR), are being implemented worldwide. Augmented reality (AR), based on virtual interactive 3-dimensional elements (holograms) overlaid in the real-world, represents a promising alternative to explore the human body. In this study, we will test the efficacy of AR as an alternative teaching method in anatomy education by comparing traditional learning methods based on 2-dimensional (2D) images, videos, and online learning programs with the novel AR learning module The primary endpoint will consist of the score in the final theoretical and practical knowledge tests, assessed at two timepoints: immediately after the study session and after 3 months. Secondary endpoints will include adverse health symptoms and user experience, assessed immediately after the study session.

Participants needed: 300
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: Balgrist University HospitalUpdated: Aug 13, 2024
Eligibility criteria

Medical students attending the 1st or 2nd year of undergraduate medical educatio... [+1]

Epilepsy [+4]

Status: Recruiting

Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Periacetabular Osteotomy

The purpose of this study is to assess the effect of Dexamethasone on postoperative pain and nausea after periacetabular osteotomy.

Participants needed: 60
Trial details
Phase: Phase 3Age: 18-99Biological sex: AllType: InterventionalSponsor: Balgrist University HospitalUpdated: Aug 12, 2024Locations: 1
Eligibility criteria

Age ≥ 18 years [+4]

Chronic pain patient, chronic lower back pain [+8]