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Condition / disease
Location
Status: Recruiting

Brain-Stomach Circuits in Chronic Nausea

The goal of this study is to determine whether stimulation of the brain-stomach connection can influence stomach activity in healthy adults and in individuals suffering from chronic nausea. The main questions it aims to answer are: * What are the best brain sites to influence the stomach? * What are the effects of different stimulation patterns on stomach activity? * Does the stimulation affect the sensation of nausea in participants suffering from chronic nausea? Researchers will use a non-invasive method of brain stimulation called Transcranial Magnetic Stimulation (TMS) and will record stomach responses with skin electrodes on the abdomen. Participants will: * Visit the clinic at least once, and for up to 9 times more over the course of several months. * Receive TMS while sitting in a chair similar to a dentist's chair. * Drink water or consume a test meal during each study visit.

Participants needed: 219
Trial details
Age: 21-60Biological sex: AllType: InterventionalSponsor: David LevinthalUpdated: Jul 24, 2026Locations: 1
Eligibility criteria

Adults between ages 21-60 years old, with and without CNVS diagnosis per self-re...

body mass index (BMI) > 30 [+15]