Clinical trials

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Condition / disease
Location
Status: Recruiting

Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia

The purpose of this clinical trial is to understand and evaluate the clinical efficacy and safety of Daphnetin Capsule in patients with vascular cognitive impairment. Changes in the Vascular Dementia Assessment Scale-cog(VADAS-cog) at 6 months were evaluated. Although Daphnetin has a dual neurovascular protective effect, however, there is still a lack of relevant high-quality studies on its role in patients with vascular cognitive impairment, especially in patients with vascular cognitive impairment in non-dementia (VCI-ND), whether it has a role in improving cognitive status needs to be urgently explored in high-quality clinical studies. Researchers are comparing Daphnetin to placebo (a drug-free analog) to see if Daphnetin is effective in treating vascular cognitive impairment. Participants will take either Daphnetin or placebo daily for six months, with follow-up visits every three months and completion of a case report form.

Participants needed: 206
Trial details
Age: 50-80Biological sex: AllType: InterventionalSponsor: First People's Hospital of ShenyangUpdated: Aug 21, 2026Locations: 1
Eligibility criteria

Be 50-80 years of age (both ends included) [+4]

Previously diagnosed dementia; vascular cognitive impairment not associated with... [+14]