Status: Recruiting
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth with overweight and obesity as well as potential mechanisms to modify disease.
Participants needed: 114
Trial details
Phase: Phase 2Age: 11-18Biological sex: AllType: InterventionalSponsor: Heba M. IsmailUpdated: Aug 21, 2026Locations: 1
Eligibility criteria
Overweight/obese youth 11-18 years of age with T1D at time of enrollment. [+1]
Known monogenic forms of diabetes or Type 2 diabetes (confirmed clinically and b... [+5]