Clinical trials

2

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Condition / disease
Location
Status: Not yet recruiting

A Study to Confirm Safety and Effectiveness of RADIESSE® Injectable Implant for the Correction of Moderate to Severe Nasolabial Folds

The purpose of this study is to confirm the long-term safety, effectiveness, and degradation profile of RADIESSE® Injectable Implant for the correction of moderate to severe nasolabial folds (NLFs) in Chinese adults. Eligible participants will receive treatment with RADIESSE® Injectable Implant in both NLFs and may receive an optional touch-up treatment at Month 1 at investigator's discretion. Participants will be followed for up to 24 months after last treatment.

Participants needed: 163
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Merz North America, Inc.Updated: Oct 5, 2026
Eligibility criteria

WSRS score of 3 (moderate) or 4 (severe) in both right and left NLFs, as determi... [+1]

Prior dermal filler or implant material detectable in the NLF area by ultrasound... [+5]

Status: Recruiting

Effectiveness and Safety of the Ulthera® System for Skin Laxity in the Lower Face, Submentum and Neck

The purpose of this study is to demonstrate superiority of treatment with the Ulthera System compared to untreated control for the improvement of skin laxity of the lower face, submental area and neck and to demonstrate the safety of treatment with the Ulthera System for the improvement of skin laxity of the lower face, submental area and neck.

Participants needed: 218
Trial details
Age: 35-65Biological sex: AllType: InterventionalSponsor: Merz North America, Inc.Updated: Jun 17, 2026Locations: 7
Eligibility criteria

Mild to moderate lower face, submental and/or neck laxity, that is amenable to i... [+4]

Scarring in area(s) to be treated. [+25]