Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Effects of RAS in SZ

The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics. The purpose of this research project is to target each patient group to examine effects of rhythmic auditory stimulation (RAS) on upper-limb movements in medicated SZ patients in a 6-month follow-up period. The main questions of this project are: 1. Does RAS reduce severity of upper-limb bradykinesia (slow movements) and dyskinesia (repetitive and involuntary movements) after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving second-generation antipsychotics? and 2. Does RAS reduce severity of upper-limb bradykinesia and dyskinesia after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving first-generation antipsychotics? Researchers will compare upper-limb movement training with the aid of RAS to upper-limb movement training without the aid of RAS to see if RAS works to improve upper-limb movements in SZ patients. Participants will: 1. Undergo an interview and movement tests and fill out questionnaires before and after the movement training program and at 3-month follow-up and 6-month follow-up; and 2. Receive movement training for 40 minutes per session for a total of 21 sessions.

Participants needed: 140
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Shu-Mei WangUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

A diagnosis of schizophrenia or schizoaffective disorder [+4]

Substance abuse or drug abuse [+10]

Status: Recruiting

Effects of RAS in Stroke

The goal of this study is to to examine whether rhythmic auditory stimulation improved movement speed, movement function of executing activities of daily living, and movement recovery of the affected upper limb, as well as quality of life in stroke patients. The main questions it aims to answer are: * Does rhythmic auditory stimulation improve movement speed in stroke patients? * Does rhythmic auditory stimulation improve movement function of executing activities of daily living in stroke patients? * Does rhythmic auditory stimulation improve movement recovery of the affected upper limb in stroke patients? * Does rhythmic auditory stimulation improve quality of life in stroke patients? Researchers will compare movement training with the aid of rhythmic auditory stimulation to movement training without the aid of rhythmic auditory stimulation to see if rhythmic auditory stimulation works to improve movement speed, movement function of executing activities of daily living, and movement recovery of the affected upper limb, as well as quality of life in stroke patients. Participants will: * Undergo movement tests and fill out questionnaires before and after the movement training program * Receive movement training for 40 minutes per session and three sessions per week for a total of 24 sessions

Participants needed: 68
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Shu-Mei WangUpdated: Jun 25, 2025Locations: 1
Eligibility criteria

(1) Diagnosed with either ischaemic or hemorrhagic stroke, and a first-time occu... [+6]

(1) Neurological diseases or medical conditions that affect upper-limb movements... [+1]