Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effect of Functional Electrical Stimulation (FES) on Handwriting Rehabilitation After Acquired Brain Injury (ABI)

Study Purpose Functional Electrical Stimulation (FES) enhances motor recovery by increasing the functional range of motion to significantly improve muscle force deficits following an acquired brain injury. While FES has shown promise in improving muscular activation, its role in facilitating fine motor skills like handwriting in the acquired brain injury population needs further investigation. The project will incorporate motion capture (mo-cap) analysis technology, which will capture participants' detailed movement patterns during handwriting tasks and provide multi-baseline pre-analysis/post-analysis of motor planning and execution for precise tracking of manual dexterity improvements by quantifying changes in fine motor control, speed, and accuracy. The study seeks to provide comprehensive evidence of FES's effectiveness in hand remediation with combined assistive technology with functional-based activity to enhance motor function and improve acquired brain injury survivors' quality of life by enabling better outcomes in daily tasks requiring fine motor skills. Functional electrical stimulation improves reaching movement in the shoulder and elbow muscles of stroke patients:

Participants needed: 36
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Texas Woman's UniversityUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Participants must have experienced either an ischemic or hemorrhagic stroke or a... [+3]

Cardiac disease to avoid potential interference with heart function during FES [+8]

Status: Not yet recruiting

Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-applied Joint Mobilization in Addition to Exercise in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

The goal of this clinical trial is to learn if a combination of patient self-administered joint mobilization and exercise works to treat knee osteoarthritis in adults. The main questions it aims to answer are: * Does self-administered joint mobilization improve the ability to perform regular daily activities? * Does self-administered joint mobilization improve knee motion? * Does self-administered joint mobilization improve hip strength? Researchers will compare the program of self-administered joint mobilization to a joint mobilization administered by a physical therapist. Participants will: * Attend 8-12 physical therapy clinic visits over 6 - 8 weeks * Perform home exercises * Visit the clinic 6 months later for a brief check-up

Participants needed: 24
Trial details
Age: 45+Biological sex: AllType: InterventionalSponsor: Texas Woman's UniversityUpdated: Jun 13, 2025Locations: 2
Eligibility criteria

Age 45 years or older [+5]

Assistive device required for ambulation [+5]

Status: Not yet recruiting

Benefits of Insoles With Real-Time Alert and Foot Self-Care Education

Novel approaches to promote adherence to diabetic footwear and prevent high incidence of diabetes foot ulcers are urgently needed. Investigators propose to translate an innovative and practical technology to supplement clinical and risk evaluation for patients with diabetes through wearable insoles and smart watch, along with foot self-care education, to improve adherence to prescribed footwear and reduce incidence of foot ulcers in those with diabetes and at risk for foot ulcers.

Participants needed: 72
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Texas Woman's UniversityUpdated: Apr 16, 2025Locations: 2
Eligibility criteria

Men or women 18 years old or older, [+4]

Active Charcot Arthropathy or major foot deformity, [+3]