Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Retinal and Choroidal Changes in Periodontal Disease

Advanced PeriodontitisIn this cross-sectional study, the relationship between periodontal disease severity and retinal and choroidal structural changes was evaluated using SD-OCT. Data from a total of 80 participants were examined. It was found that choroidal thickness increased and ganglion cell layer thickness decreased as periodontal disease severity increased, while no significant relationship was found in RNFL and IPL thicknesses. The findings support a possible association between periodontal disease and ocular structural changes.

Participants needed: 80
Trial details
Age: 20-54Biological sex: AllType: ObservationalSponsor: Zeliha Başak Çakır ErdilUpdated: Oct 5, 2026Locations: 1Duration: 1 Day
Eligibility criteria

Not listed

Status: Recruiting

Root Coverage Performance of Restorative Materials in Class V Cavities

This prospective randomized controlled clinical trial aims to evaluate the influence of different restorative materials placed in Class V cervical lesions on the clinical outcomes of root coverage surgery using a subepithelial connective tissue graft. Patients with Cairo RT1 (Miller Class I-II equivalent) gingival recession associated with non-carious cervical lesions or existing cervical restorations will receive one of the restorative approaches according to the study protocol. Clinical parameters, including the percentage of root coverage and soft tissue stability, will be evaluated during follow-up to determine which restorative approach provides the most favorable clinical outcome.

Participants needed: 30
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Zeliha Başak Çakır ErdilUpdated: Jul 7, 2026Locations: 1
Eligibility criteria

Age younger than 18 years. Pregnancy or breastfeeding. Poor oral hygiene. Uncont...