Clinical trials

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Condition / disease
Location
Status: Recruiting

Exosome Therapy for Male Androgenetic Alopecia

The goal of this clinical trial is to learn if local scalp injection of human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) can treat androgenetic alopecia (AGA) in male patients with AGA. The main question it aims to answer is: Does hUCMSC-Exos injection improve hair regrowth compared with placebo? Researchers will compare hUCMSC-Exos injection to placebo injection to see if hUCMSC-Exos leads to superior efficacy in hair follicle regeneration, as measured by changes in hair density, hair thickness, and patient-reported outcomes. Participants will: Receive randomized, double-blinded local scalp injections of either hUCMSC-Exos or placebo Attend scheduled follow-up visits for hair assessment and safety monitoring Undergo photography, trichoscopy, and complete quality-of-life or psychosocial burden questionnaires as applicable

Participants needed: 120
Trial details
Phase: Phase 2Age: 18-55Biological sex: MaleType: InterventionalSponsor: Zhang HanUpdated: Jul 9, 2026Locations: 1
Eligibility criteria

Male subjects aged 18 to 55 years; [+3]

Other types of alopecia, including alopecia areata, cicatricial alopecia, or tel... [+7]