Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H

ConditionsHealthy Healthy Adult High Altitude Effects High Altitude Heart Rate Variability (HRV)ECG Abnormalities

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-80

SponsorSilvia Ulrich Somaini

About this trial

To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level and re-ascent from sea level to 2850m on heart rate variability and other hemodynamic parameters in healthy individuals, who live permanently \>2600m.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged 18-80 years and of all genders

Permanent residence > 2600 m

healthy: no self perceived cardiopulmonary disease limiting daily activities

written informed consent to participate in the study.

Disqualifiers

Age <18 years or >80 years

Participants who cannot follow the study investigations

Participants permanently living < 2600m

Participants who traveled and stayed overnight at altitudes <2000 m in the past 4 weeks.

Trial design

Design model

Single group

Treatments tested in this trial

Descent and re-ascent (2850m, sea level)
Behavioral
Descent from 2850m to sea level (in one day by bus) and re-ascent after 7 days from sea level to 2850m (in one day by bus)

Treatment groups

14 Participants

are divided into 1 treatment group

Group A: Heart rate variability HRV during descent and re-ascentExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Heart rate variability HRV during descent and re-ascent

Difference/change in heart rate variability at different altitudes during descent (2850m to sea level) and during re-ascent after 7 days (sea level to 2850m) in healthy individuals

Time frame