Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals

ConditionsHealthy Healthy Adult High Altitude Effects High Altitude Lung Function Tests Lung Function Changes

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-80

SponsorSilvia Ulrich Somaini

About this trial

To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live permanently \> 2600m.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged 18-80 years and of all genders

Permanent residence > 2600 m

healthy: no self perceived cardiopulmonary disease limiting daily activities

written informed consent to participate in the study.

Disqualifiers

Age <18 years or >80 years

Participants who cannot follow the study investigations

Participants permanently living < 2600m

Participants who traveled and stayed overnight at altitudes <2000 m in the past 4 weeks.

Trial design

Design model

Single group

Treatments tested in this trial

Re-ascent from sea level to 2850m
Behavioral
Descent from 2850m to sea level with a stay for 7 days and re-ascent/return back to their usual living altitude at 2850m

Treatment groups

14 Participants

are divided into 1 treatment group

Group A: Lung function at sea level and at 2850mExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

FEV1 after re-ascent to 2850m

Difference/change in forced expiratory volume in one second FEV1 between sea level (measurement on the 4th day) and day after re-ascent to 2850m in healthy individuals

Time frame