To study the effect of descent from high altitude (Quito Ecuador: 2850m) to sea level on six-minute walking distance and scores in healthy individuals, who live permanently \>2600m.
Adults aged 18-80 years and of all genders
Permanent residence > 2600 m
healthy: no self-perceived cardiopulmonary disease limiting daily activities
written informed consent to participate in the study
Age <18 years or >80 years
Participants who cannot follow the study investigations
Participants permanently living < 2600m
Participants who traveled and stayed overnight at altitudes <2000 m in the past 4 weeks.
Single group
Descent from 2850m to sea level
BehavioralDescent from 2850m to sea level with stay for 7 days
Six-minute walking distance after 7 days at sea level
Difference/change in six-minute walking distance in meter (6MWD) between 2850m and Day 5-7 at sea level in healthy individuals
SpO2 (%) at rest and end-exercise after 7 days at sea level
Difference/change in SpO2 (peripheral oxygen saturation) at rest and end-exercise between 2850m and Day 5-7 at sea level in healthy individuals
Heart rate (beats per minute) at rest and end-exercise after 7 days at sea level
Difference/change in heart rate at rest and end-exercise between 2850m and Day 5-7 at sea level in healthy individuals
Blood pressure (mmHg) at rest and end-exercise after 7 days at sea level
Difference/change in blood pressure at rest and end-exercise between 2850m and Day 5-7 at sea level in healthy individuals
Dyspnea and leg discomfort sensation after 7 days at sea level
Difference/change in dyspnea and leg discomfort sensation (assessed with BORG-CR10-Scale, Category Rating 0-10 with 10 being the most dyspnea/leg discomfort) at rest and end-exercise between 2850m and 5-7 days at sea level in healthy individuals
Click on the lead sponsor to view all of their trials.
Silvia Ulrich Somaini
Lead sponsor
University of Zurich
Sponsor institution
This trial is not recruiting at the moment. You can still explore other options:
