Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH

ConditionsPulmonary Arterial Hypertension (PAH)Pulmonary Vascular Disease Six-minute Walk Test High Altitude Effects High Altitude

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-80

SponsorSilvia Ulrich Somaini

About this trial

To study the effect of relocation from high altitude (Quito: 2850m) to sea level on six-minute walking distance and scores in patients with pulmonary arterial hypertension PAH, who live permanently \>2600m.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult patients aged 18-80 years and of all genders

Permanent residence > 2600 m

Diagnosis of pulmonary arterial hypertension PAH (PAHHA-Group) according to guidelines

Patients are stable on therapy

Disqualifiers

Age <18 years or >80 years

unstable condition

Patients who cannot follow the study investigations

Patient permanently living < 2600m

Trial design

Design model

Single group

Treatments tested in this trial

Descent from 2850m to sea level
Behavioral
Descent from 2850m to sea level with stay for 7 days

Treatment groups

20 Participants

are divided into 1 treatment group

Group A: Six-minute walking distance 6MWD at 2850m and at sea levelExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Six-minute walking distance (m) after 7 days at sea level

Difference/change in six-minute walking distance 6MWD between 2850m and Day 5-7 at sea level in patients with pulmonary arterial hypertension

Time frame