Classic Versus Interfascial Axillary Block in Hand, Wrist, and Forearm Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorBursa Yuksek Ihtisas Training and Research Hospital

About this trial

Hand, wrist, and forearm surgeries are commonly performed procedures with significant postoperative pain potential. Regional anesthesia of the brachial plexus via the axillary approach is one of the gold-standard techniques for distal upper-limb surgery. In the conventional (classic) axillary block, the median, ulnar, and radial nerves within the axillary sheath are individually targeted under ultrasound guidance; however, anatomical septations around the axillary artery may prevent homogeneous spread of local anesthetic, leading to a patchy block and reduced intraoperative success.

The interfascial axillary block is a modified approach in which local anesthetic is deposited into the fascial planes between the axillary muscles rather than directly into the nerve sheath, aiming for passive diffusion, homogeneous spread, and fewer needle manipulations. This prospective, randomized, single-center study compares the classic axillary block with the interfascial axillary block in patients undergoing hand, wrist, and forearm surgery, primarily in terms of surgical anesthesia adequacy (block success).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged 18-90 years

American society of anesthesiologists physical status I-II-III

Scheduled for elective hand, wrist, or forearm surgery

Written informed consent obtained

Disqualifiers

History of local anesthetic allergy

Coagulation disorder

BMI > 40 kg/m²

Infection at the block site

Trial design

Design model

Parallel

Treatments tested in this trial

  • Classic Axillary Block

    Procedure/Surgery

    Classic (perivascular/perineural) axillary brachial plexus block

  • Interfascial Axillary Block

    Procedure/Surgery

    Interfascial (fascial-plane) axillary brachial plexus block.

Treatment groups

110 Participants
are divided into 2 treatment groups
Group A: Classic Axillary BlockActive comparator 1 intervention
Group B: Interfascial Axillary BlockActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Surgical anesthesia adequacy (block success)

Complete sensory and motor blockade of the surgical field, allowing the operation to be completed without additional local infiltration or conversion to general anesthesia

Time frame
30 minutes after block

Secondary outcomes

1

Block application time

time from needle insertion to withdrawal.

Time frame
intraoperative
2

Sensory block onset time

Pin-Prick test in the median, ulnar, radial, and musculocutaneous dermatomes (0: normal, 1: blunt, 2: no sensation).

Time frame
5., 10., 15., 30. minutes
3

Motor block onset time

Time frame
5., 10., 15., 30. minutes
4

Intraoperative additional analgesic/sedation consumption

Time frame
intraoperative

Other outcomes

Sponsors and contacts

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