Cone Evasion Walk Test in Multiple Sclerosis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorHacettepe University
About this trial
This cross-sectional methodological study aims to examine the test-retest reliability, intrasession reliability, and construct validity of the Cone Evasion Walk (CEW) Test in individuals diagnosed with Multiple Sclerosis (MS). The CEW test is a performance-based clinical assessment that evaluates dynamic balance, obstacle avoidance, and fall risk by quantifying the number of cones contacted during a standardized walking task. Although the psychometric properties of the CEW test have been established in populations including stroke survivors, patients with knee osteoarthritis, and patients with hip osteoarthritis, no study has yet investigated its measurement properties in individuals with MS. Given the multifaceted nature of gait and balance impairments in MS - encompassing motor, sensory, cognitive, and visuospatial deficits - the CEW test may serve as a clinically meaningful and ecologically valid tool in this population. Participants will be recruited from the Department of Neurology at Erciyes University Hospital and will undergo the CEW test along with a comprehensive battery of established mobility and balance outcome measures.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
The study population will consist of adults with a confirmed diagnosis of multiple sclerosis who meet the predefined eligibility criteria. Participants will be recruited from individuals with multiple sclerosis and will undergo the Cone Evasion Walk Test and standardized clinical assessments to investigate the reliability and validity of the test in this population.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Cone Evasion Walk Test and Clinical Assessments
Diagnostic testThe Cone Evasion Walk Test is a performance-based walking assessment designed to evaluate the ability to negotiate and evade obstacles during walking. The test will be administered to individuals with multiple sclerosis to investigate its reliability and validity.
Treatment groups
50 Participants
are divided into 1 treatment groupGroup A: Individuals with Multiple Sclerosis1 intervention
Trial outcomes
Primary outcomes
1
Test-retest Reliability of the Cone Evasion Walk Test
Test-retest reliability of the Cone Evasion Walk (CEW) Test assessed using the intraclass correlation coefficient (ICC, two-way mixed model, absolute agreement) between two test sessions administered 3 to 7 days apart. The total number of cones touched during the walk test will be recorded as the primary score.
Time frame
Baseline and 3-7 days after baseline assessmentSecondary outcomes
1
Expanded Disability Status Scale (EDSS)
The Expanded Disability Status Scale (EDSS) will be used to assess the overall level of neurological disability in individuals with multiple sclerosis. The EDSS provides a standardized measure of disability ranging from 0 to 10, with higher scores indicating greater disability. The EDSS will be used to examine the relationship between overall MS-related disability and performance on the Cone Evasion Walk Test.
Time frame
Baseline assessment.2
Timed 25-Foot Walk Test (T25FW)
The Timed 25-Foot Walk Test (T25FW) will be used to assess walking speed and ambulatory function in individuals with multiple sclerosis. Participants will be instructed to walk a 25-foot (7.62-meter) distance as quickly and safely as possible. The time required to complete the walk will be recorded in seconds. Lower completion times indicate better walking performance. The T25FW will be used to examine the relationship between established ambulatory performance and Cone Evasion Walk Test performance.
Time frame
Baseline assessment.3
Dynamic Gait Index (DGI)
The Dynamic Gait Index (DGI) will be used to assess dynamic gait performance and the ability to adapt walking to changing task and environmental demands in individuals with multiple sclerosis. The DGI consists of eight walking tasks, including changes in gait speed, horizontal and vertical head movements, pivot turning, stepping over and around obstacles, and stair negotiation. Each item is scored from 0 to 3, yielding a total score ranging from 0 to 24, with higher scores indicating better dynamic gait performance.
Time frame
Baseline assessment.4
Symbol Digit Modalities Test (SDMT)
The Symbol Digit Modalities Test (SDMT) will be used to assess information processing speed and cognitive efficiency in individuals with multiple sclerosis. Participants will be asked to match geometric symbols with corresponding numbers according to a provided key within a specified time period. Higher scores indicate better information processing speed. The SDMT will be used to examine the relationship between cognitive processing speed and Cone Evasion Walk Test performance.
Time frame
Baseline assessment.Sponsors and contacts
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Hacettepe University
Lead sponsor
Bozok University
Sponsor institution
Source ClinicalTrials.gov
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