Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorSohag University
About this trial
This study evaluates corneal epithelial thickness using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors. It aims to assess the relationship between epithelial thickness patterns and different types of refractive errors.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥ 18 years-
Patients diagnosed with myopia or hyperopia by refraction
Clear cornea with no evidence of corneal pathology
Ability to undergo reliable anterior segment imaging
Disqualifiers
Inability to fixate or follow instructions
Family history of keratoconus
Glaucoma,Cataract
Previous ocular surgery including refractive surgery
Trial population
Adult participants (≥18 years) with refractive errors, including myopia, hyperopia, and astigmatism, as well as emmetropic subjects, recruited from the Ophthalmology Department and undergoing anterior segment optical coherence tomography (AS-OCT) examination.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
360 Participants
are grouped into 1 trial groupGroup A: All Participants
Trial outcomes
Primary outcomes
1
Measurement of corneal epithelial thickness using AS-OCT
Corneal epithelial thickness will be measured using anterior segment optical coherence tomography (AS-OCT). Measurements will include central and regional epithelial thickness values in microns in patients with different refractive errors.
Time frame
At baseline during a single study visit when participants undergo AS-OCT examination.Secondary outcomes
1
Comparison of epithelial thickness between myopic and hyperopic eyes
Corneal epithelial thickness will be compared between myopic and hyperopic eyes using AS-OCT measurements.
Time frame
At baseline (single visit)2
Comparison of epithelial thickness in eyes with and without astigmatism
Corneal epithelial thickness will be evaluated and compared between eyes with astigmatism and those without astigmatism using AS-OCT.
Time frame
At baseline (single visit)3
Corneal epithelial thickness asymmetry across corneal regions and inter-eye comparison
Epithelial thickness will be assessed across different corneal regions and compared between both eyes to evaluate inter-eye asymmetry.
Time frame
At baseline (single visit)4
Comparison of epithelial thickness in low and high refractive errors
Corneal epithelial thickness profiles will be compared between low and high degrees of myopia and hyperopia using AS-OCT measurements.
Time frame
At baseline (single visit)Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: