Early Detection of Initial Caries Using Fluorescent Starch Nano-particles Compared With Salivary Biomarkers

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorMenoufia University

About this trial

Dental caries is one of the most prevalent chronic oral diseases worldwide and remains a major public health concern. The disease begins with microscopic demineralization of enamel, which is reversible if diagnosed at an early stage. Therefore, early detection of carious lesions is essential to implement preventive and minimally invasive treatment strategies before irreversible tooth destruction occurs.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Cavitated carious lesions

Previous restorative treatment on the examined tooth

Antibiotic therapy during the previous month,

Systemic diseases affecting salivary secretion

Trial design

Design model

Parallel

Treatments tested in this trial

  • Fluorescent Starch Nano-particles

    Procedure/Surgery

    The evaluation of the diagnostic accuracy of LumiCare mouth rinse combined with salivary biomarkers for the early detection of initial enamel caries and to compare its diagnostic performance with conventional clinical diagnostic methods.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Group A: Caries GroupActive comparator 1 intervention
Group B: Group B: Control GroupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Diagnosis of Initial Caries

Evaluation of the participants by Using Fluorescent Starch Nano-particles and Salivary Biomarkers in early detection of initial caries

Time frame
immediately after the intervention

Secondary outcomes

Other outcomes

Sponsors and contacts

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