About this trial
Atelectasis is considered a common complication in the perioperative period, especially following surgeries under general anesthesia. Postoperative atelectasis could occur anytime during the perioperative period from intraoperative period to 24 hours postoperative and contribute to a variety of other complications, including hypoxemia and pneumonia. In the literature, several methods were utilized to combat this phenomenon, therefore, we investigate the role of intraoperative salbutamol in reducing the incidence of atelectasis. It is well known that salbutamol could be an adjunctive bronchodilator medication used in the intraoperative anesthetic regimens.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
The study will include patients aged 18-70 years
American Society of Anesthesiologists (ASA) physical status of I or II
Will undergo thoracic, abdominal or spinal surgery
Disqualifiers
cardiac conditions other than hypertension like arrhythmia
previous cardiac surgeries and valvular heart diseases
Trial design
Parallel
Treatments tested in this trial
Salbutamol (Ventolin®)
Drug-4 puffs of salbutamol (each puff = 100 µg, total dose 200-400 µg)
Treatment groups
Trial outcomes
Primary outcomes
Postoperative atelectasis (vital signs)
All patients will undergo a thorough medical history, appropriate physical examination, and relevant investigations according to their clinical needs. Particular attention will be given to vital signs, especially pulse oximetry.
Postoperative atelectasis (x-ray)
All patients will undergo a chest X-ray to investigate for atelectasis.
Postoperative atelectasis (blood gases)
Postoperatively blood gases will be assessed to investigate for atelectasis. This will be done through arterial blood gases sample at 24 hours postoperative.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
King Abdullah University Hospital
Lead sponsor
Jordan University of Science and Technology
Sponsor institution
Jordan University of Science and Technology
Collaborator
This trial is not recruiting at the moment. You can still explore other options: