Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-45
SponsorCairo University
About this trial
BACKGROUND:
Anterior cruciate ligament (ACL) is an important ligamentous structure in the knee joint which contributes in maintaining stability. ACL injury contribute to approximately 50% of knee injuries .The incidence of ACL ruptures is estimated to be between 30 and 78 per 100,000 people per year .
The incidence of ACL ruptures varies depending on a number of factors, including age, sex, sport participation, and genetics. ACL ruptures are most common in young adults, particularly women. The risk of an ACL rupture has been reported as 2-8 times higher for women than for men. A systematic review study found that the risk of ACL injury was highest in football, followed by soccer, basketball, and skiing .
Nowadays, Peroneus longus tendon (PLT) autograft is used in orthopaedic surgeries. Some studies reported that PLT graft had maintained a possible more efficient ACL substitute for its tensile strength and regeneration ability after being inserted post-surgery . The PLT graft has additional benefit as it does not cause secondary injury to the knee and its adjacent structures .
Ankle proprioception is one of the crucial components contributing to postural control . PLT graft for ACL reconstruction might affect the already compromised body balance by influencing postural stability and ankle stability at the donor ankle site. So, this study will be conducted to assess and compare the effect of ACLreconstruction with PLT graft to the effect of ACL reconstruction with HT graft on ankle stability and postural control .
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ranging between 15- 45 years
Having unilateral isolated ACL tear with no concomitant tear of other ligaments of the knee
Having no evidence of meniscal repair
Having bilateral healthy ankle before surgery.
Disqualifiers
Pre-existing ankle injury or ankle instability
Associated ligament injury, chondral damage, meniscal injury, fracture around the knee, and presence of pathologic condition in the lower extremity or an abnormal contralateral knee joint.
Visible mal-alignments in the lower extremities.
Previous surgery to the affected knee.
Trial design
Design model
Parallel
Treatments tested in this trial
Isokinetic and functional balance tests
Other interventionIsokinetic and functional balance tests
Treatment groups
40 Participants
are divided into 2 treatment groupsGroup A: Peroneus longus autograft groupActive comparator 1 intervention
Group B: hamstring autograft groupActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Peak torque of plantarflexors and evertors (N.m)
The isokinetic strength of ankle muscles will be evaluated at angular velocities of 30°/s and 120°/s in concentric/concentric mode for the ankle Planter flexion/dorsiflexion and in concentric/eccentric reciprocal action for the ankle eversion/eversion
Time frame
preoperative /3 months / 6 months2
Star Excursion Balance Test distance (cm)
The Modified version of the Star Excursion Balance Test with only three directions (anterior, posterolateral \[PL\], and posteromedial \[PM\]) will be used . The patient will be given four practice trials to familiarize themselves with the task, followed by a brief rest. Then, three trials will be recorded with at least 10 seconds of rest between each trial. The average of the three trials will be normalized to the participant's leg length and used for analysis.
Time frame
preoperative /3 months / 6 months3
Single leg stance time (sec)
The procedure will be repeated three times
Time frame
preoperative /3 months / 6 monthsSponsors and contacts
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Source ClinicalTrials.gov