Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-90
SponsorRen Da
About this trial
This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing ERCP.
Participants will be randomly assigned to receive either esketamine or sufentanil during sedation. Researchers will monitor blood oxygen levels, blood pressure, and recovery time during and after the procedure to evaluate safety and effectiveness.
Eligibility criteria
Qualifiers
Adults aged ≥18 years
Patients scheduled to undergo endoscopic retrograde cholangiopancreatography (ERCP)
American Society of Anesthesiologists (ASA) physical status I-III
Body mass index (BMI) between 18.5 and 30 kg/m²
Disqualifiers
Allergy or contraindication to propofol, esketamine, sufentanil, or related medications
Severe hypertension (systolic blood pressure ≥180 mmHg and/or diastolic blood pressure ≥110 mmHg)
Severe dysfunction of the heart, lungs, liver, or kidneys
History of central nervous system disorders or psychiatric disorders
Trial design
Treatments tested in this trial
- Esketamine
- Sufentanil
Treatment groups
530 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Ren Da
Lead sponsor
Beijing Friendship Hospital
Sponsor institution
Source ClinicalTrials.gov