Biliary Tract Diseases

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Review clinical trials related to Biliary Tract Diseases. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCP

This study compares two anesthesia medications, esketamine and sufentanil, used together with propofol during ERCP procedures. The goal is to find out which combination provides better safety and comfort for people undergoing ERCP. Participants will be randomly assigned to receive either esketamine or sufentanil during sedation. Researchers will monitor blood oxygen levels, blood pressure, and recovery time during and after the procedure to evaluate safety and effectiveness.

Participants needed: 530
Trial details
Age: 18-90Biological sex: AllType: InterventionalSponsor: Ren DaUpdated: Jul 14, 2026
Eligibility criteria

Adults aged ≥18 years [+5]

Allergy or contraindication to propofol, esketamine, sufentanil, or related medi... [+7]

Status: Not yet recruiting

Outcomes After Liver and Biliary Resection at a High-Volume Center

The goal of this observational study is to evaluate clinical and oncologic outcomes in adult patients undergoing liver and/or biliary resection for benign and malignant diseases. This study evaluates postoperative morbidity and mortality within 90 days after surgery, as well as overall survival and disease-free survival in patients with malignant disease. Participants will: * undergo standard surgical and perioperative management according to routine clinical practice * have clinical, surgical, and follow-up data collected from institutional medical records * be followed for postoperative outcomes and long-term oncologic outcomes up to 5 years

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Azienda USL Toscana CentroUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years [+4]

Age < 18 years [+4]

Status: Not yet recruiting

SmartGlass-Guided ERCP with Cannulation of Native Papilla 1.0

The aim of this prospective randomized study is to evaluate whether telemedical assistance via SmartGlasses is equivalent to physical presence in teaching Endoscopic Retrograde Cholangiopancreaticography (ERCP) in terms of examination success and safety. Endoscopic papilla cannulation is a key skill for successful ERCP and therefore a measurable primary endpoint of the study. This can be measured as the time (in seconds/minutes) between stable visualization of the papilla and successful endoscopic cannulation of the target structure (bile duct or pancreatic duct).

Participants needed: 170
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Helios Kliniken SchwerinUpdated: Nov 12, 2024Locations: 1
Eligibility criteria

Adult patients aged ≥ 18 years without previous papillotomy

Cannulation of the minor papilla necessary [+5]

Status: Not yet recruiting

Construction of Multicenter Retrospective Registry Cohort Database for Gallbladder Cancer

The aim of the study is to establishing a standardized clinical information database for patients with malignant tumors of gallbaldder. Based on the database, real-world clinical research on the diagnosis and treatment of biliary tract tumors is about to be carried out, and a high-standard cohort research foundation is laid for precision therapy.

Participants needed: 5,000
Trial details
Age: 18-74Biological sex: AllType: ObservationalSponsor: RenJi HospitalUpdated: Feb 28, 2024
Eligibility criteria

Sign informed consent, have good compliance, and be willing to accept follow-up... [+4]

Patients with gallbladder cancer, gallbladder cancer foci are not primary lesion... [+4]

Status: Not yet recruiting

The Construction of Clinical Database and Multiomics Biobank Based on a Multicentral Prospective Cohort of Benign and Malignant Biliary Tract Diseases

The aim of the study is to establishing a standardized biobank and a clinical information database for patients with benign and malignant tumors of the biliary system. With follow-up plans and advanced multiomics technology, a multiomics database for patients with benign and malignant tumors of the biliary tract will be further established. Based on the above work, real-world clinical research on the diagnosis and treatment of biliary tract tumors is about to be carried out, and a high-standard cohort research foundation is laid for precision therapy based on multiomics characteristics and molecular typing of biliary tract tumors.

Participants needed: 500
Trial details
Age: 18-74Biological sex: AllType: ObservationalSponsor: RenJi HospitalUpdated: Jun 9, 2023Duration: 2 Years
Eligibility criteria

Sign informed consent, have good compliance, and be willing to accept follow-up... [+4]

Patients with biliary malignant tumors, biliary malignant tumor foci are not pri... [+4]