Health TrialsbyHealthPanel

Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement

ConditionsAlveolar Bone LossAlveolar Ridge AugmentationDental Implant
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCairo University

About this trial

CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted. Autologous bone chips will be harvested via bone scraping and used for augmentation, CGF membranes will be placed over the grafted area. Suturing of the mucoperiosteal flap. Radiographic evaluation of the bone density and tissue thickness will be performed by CBCT preoperatively, immediate postoperative and after the procedure by 4 months. Clinical evaluation of the tissue thickness using periodontal probe preoperatively, immediate postoperatively and after the procedure by 4 months

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).

Presence of active or untreated periodontal disease.

Vertical root fractures involving the buccal aspect.

Tooth /teeth with horizontal fractures below bone level.

Disqualifiers

Presence of active or untreated periodontal disease.

Vertical root fractures involving the buccal aspect.

Tooth /teeth with horizontal fractures below bone level.

Tooth /teeth with external or internal resorption.

Trial design

Design model

Single group

Treatments tested in this trial

  • concentrated growth factor (CGF) Membrane

    Other intervention

    This is a third-generation autologous blood concentrate prepared using a dedicated centrifuge system. The process creates a fibrin-rich organic matrix from the patient's own blood, which is then molded into a membrane and packed over the grafted bone to enhance bone density increase and improvement of the surrounding tissue.

Treatment groups

8 Participants
are divided into 1 treatment group
Group A: GTR with Autogenous Bone Chips and CGF MembraneOther 1 intervention

Trial outcomes

Primary outcomes

1

tissue biotype

using periodontal probe to measure gingival thickness

Time frame
preoperative, immediate postoperative and 4 months after the procedure

Secondary outcomes

1

bone density

cbct xray

Time frame
preoperative, immediately postoperative, and 4 months after the surgery
2

patient satisfaction

psq18 is a chart where the patient describes the level of their satisfaction

Time frame
after 4 months from the surgery

Other outcomes

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

Cairo University Status unavailable 12511, Giza, Cairo GovernorateEgyptEgypt

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: