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Modified Guarnieri-Desarda Technique Versus Lichtenstein Technique in Inguinal Hernia Repair

ConditionInguinal Hernia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorCairo University

About this trial

The aim of this study is to compare the surgical outcome of both Lichnichtien tension free mesh hernioplasty of inguinal hernia and the combined modified Guarnieri Desarda technique in terms of postoperative pain, post operative complications (seroma, hematoma, wound infection), chronic inguinodenia, early recurrence and assessment of testicular vascularity and size by application of a testicular duplex and ultrasound.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult male patients aged 18 years or older.

Patients diagnosed with non-complicated inguinal hernia (both direct and indirect).

Patients able to provide written informed consent to participate in the study.

Disqualifiers

Patients younger than 18 years old.

Patients with complicated hernias (e.g., inflamed, obstructed, or strangulated hernias).

Patients with a recurrent inguinal hernia.

Patients with weak or thin external oblique aponeurosis (intraoperative findings).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Lichtenstein Mesh-Based Hernioplasty

    Procedure/Surgery

    This is a tension-free hernioplasty procedure that uses a synthetic mesh to reinforce the inguinal canal floor. The mesh is fixed to the inguinal ligament and internal oblique aponeurosis, creating a barrier to prevent hernia recurrence. It is considered the gold standard for inguinal hernia repair and is widely used for its effectiveness in reducing recurrence rates and postoperative complications.

  • Combined Modified Guarnieri-Desarda Tissue-Based Hernioplasty

    Procedure/Surgery

    This technique combines elements of the Guarnieri and Desarda tissue-based repairs. It does not involve the use of synthetic mesh, relying instead on the patient's own tissues to reinforce the inguinal canal. The Guarnieri technique reshapes the internal ring to improve the inguinal canal's shutter mechanism, while the Desarda technique reinforces the posterior wall using the external oblique aponeurosis. This approach aims to preserve natural anatomy and minimize complications associated with mesh use.

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: Lichtenstein Mesh-Based RepairActive comparator 1 intervention
Group B: Combined Modified Guarnieri-Desarda Tissue-Based RepairExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Postoperative Pain Assessment

Postoperative pain will be evaluated using the Mankoski Pain Scale (0-10). Pain scores will be recorded at different time intervals to assess immediate and long-term postoperative pain, with scores from 0 to 2 considered negligible, and scores from 3 to 10 considered significant.

Time frame
At 2 weeks, 1 month, 3 months, and 6 months post-surgery.

Secondary outcomes

1

Incidence of Postoperative Complications

The occurrence of postoperative complications such as seroma, hematoma, wound infection, and testicular complications (e.g., hydrocele, cord induration) will be recorded and analyzed for each group.

Time frame
At 2 weeks, 1 month, and 3 months post-surgery.
2

Hernia Recurrence Rate

The rate of hernia recurrence will be assessed through clinical examination and imaging, comparing recurrence between the Lichtenstein mesh-based repair group and the modified Guarnieri-Desarda tissue-based repair group.

Time frame
At 6 months and 1 year post-surgery.
3

Testicular Vascularity

Testicular vascularity will be evaluated using testicular duplex and ultrasound, comparing any changes pre- and post-surgery between the two groups.

Time frame
At 3 months post-surgery.

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Cairo University

Lead sponsor

Source ClinicalTrials.gov
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