Physical Activity During Hospitalization and Hospital-Associated Disability

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorHvidovre University Hospital

About this trial

This study examines physical activity during and after hospitalization in acutely hospitalized older adults and its association with hospital-associated disability (HAD).

Older adults have low levels of physical activity during acute hospitalization, which is associated with an increased risk of HAD. HAD is a decline in the ability to perform activities of daily living that occurs in relation to hospitalization and cannot be explained by the acute illness alone. HAD affects up to 30% of acutely hospitalized older adults and is associated with adverse outcomes, including an increased risk of discharge to a nursing home, readmission, and mortality. Furthermore, patients who develop HAD are at risk of not regaining their pre-admission functional level and experiencing persistent functional decline after discharge.

Physical activity and exercise are recommended as strategies to prevent HAD. However, many acutely hospitalized older adults have limited capacity or motivation to engage in structured exercise. It therefore remains unclear how much physical activity during hospitalization is sufficient to reduce the risk of HAD and which types of physical activity patients are able and prefer to perform. The study will also examine patients' ability and preferences for different types of physical activity during hospitalization and explore their motivation, barriers, and preferences for physical activity after discharge.

The results may help identify clinically relevant levels of physical activity during hospitalization and contribute to more patient-centered approaches to supporting physical activity and preventing functional decline during and after hospitalization.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Aged 65 years or older

Acutely admitted to the Department of Geriatrics or the Department of Cardiology

Disqualifiers

In isolation

Delirium

Unable to provide informed consent

Unable to speak and understand Danish

Trial population

Older adults (65 years or older) acutely admitted to the Department of Geriatrics or the Department of Cardiology at Copenhagen University Hospital, Hvidovre.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Physical Activity During and After Hospitalization

    Other intervention

    Participants will receive standard care throughout hospitalization. In addition to standard care, participants will take part in a single supervised assessment of their ability and preferences for different types of physical activity. The assessment includes hallway walking (200 steps, with walking aids or assistance if needed) and resistance exercise consisting of three sets of 8-12 repetition maximum sit-to-stands. Participants will also be asked about their preference for group-based functional training and about their motivation and barriers related to physical activity. Physical activity will be objectively measured using SENS motion® sensor technology continuously during hospitalization and for seven consecutive days prior to the 8-week follow-up after discharge. Self-reported mobility during hospitalization will also be assessed. After discharge, participants' experiences, motivation, barriers, and preferences related to physical activity and rehabilitation will be explored th

Treatment groups

170 Participants
are divided into 1 treatment group
Group A: Acutely Hospitalized Older Adults1 intervention

Trial outcomes

Primary outcomes

1

Hospital-associated disability

Hospital-associated disability (HAD) is defined as a new decline in functional independence in at least one activity compared with the participant's pre-admission level. Functional independence is assessed using three components: six basic activities of daily living from the Katz Index (bathing, dressing, toileting, transferring, continence, and feeding); five instrumental activities of daily living inspired by the Lawton IADL Index (shopping, housekeeping, laundry, food preparation, and medication management); and four mobility-related activities (walking 400 meters without rest, climbing or descending one flight of stairs without rest, carrying 5 kg, and driving a car). Each activity is scored as unable to perform (0), able to perform with assistance (1), or able to perform independently (2). Participants with a decline in independence in at least one activity compared with their retrospectively assessed pre-admission level are classified as having HAD.

Time frame
At inclusion and 1, 4 and 8 weeks after discharge
2

Imagined ability to perform physical activity during hospitalization

Participants' imagined ability to perform physical activity during hospitalization will be assessed by asking whether they can imagine performing the activity daily during hospitalization. Imagined ability will be assessed for hallway walking (200 steps) and resistance exercise (three sets of 8-12 sit-to-stand repetitions) and group-based functionel training.

Time frame
At inclusion
3

Actual ability to perform physical activity during hospitalization

Participants' actual ability to perform physical activity during hospitalization will be assessed by asking them to perform hallway walking (200 steps) and resistance exercise (three sets of 8-12 sit-to-stand repetitions). For each activity, actual ability will be categorized as able to complete the activity as defined, 0) unable to complete the activity, 1) able to complete the activity with assistance and 2) able to complete the activity independently. Reasons for inability to complete an activity will be recorded.

Time frame
At inclusion
4

Preferred type of physical activity during hospitalization

Participants will be asked which type of physical activity they prefer: hallway walking, resistance training and group-based functional training. (Group-based functional training will be assessed as a preference only and will not be physically performed as part of the assessment).

Time frame
At inclusion

Secondary outcomes

1

Mean Daily steps

Number of daily steps assessed by a SENS motion® accelerometer worn continuously from inclusion and throughout hospitalization and for seven consecutive days prior to the 8-week follow-up after discharge. A measurement day is considered valid if more than 20 hours of 24-hour mobility data are available. For each participant, mean daily step count is calculated across all available valid days within each measurement period.

Time frame
From inclusion through hospital discharge, an average of 5 days; and 7 consecutive days before the 8-week follow-up
2

Mean daily uptime

Daily time spent in uptime assessed by a SENS motion® accelerometer worn continuously from inclusion and throughout hospitalization and for seven consecutive days prior to the 8-week follow-up after discharge. A measurement day is considered valid if more than 20 hours of 24-hour mobility data are available. For each participant, mean daily step count is calculated across all available valid days within each measurement period.

Time frame
From inclusion through hospital discharge, an average of 5 days; and 7 consecutive days before the 8-week follow-up
3

Mean daily walking

Daily time spent walking assessed by a SENS motion® accelerometer worn continuously from inclusion and throughout hospitalization and for seven consecutive days prior to the 8-week follow-up after discharge. A measurement day is considered valid if more than 20 hours of 24-hour mobility data are available. For each participant, mean daily step count is calculated across all available valid days within each measurement period.

Time frame
From inclusion through hospital discharge, an average of 5 days; and 7 consecutive days before the 8-week follow-up
4

Mean daily standing

Daily time spent standing assessed by a SENS motion® accelerometer worn continuously from inclusion and throughout hospitalization and for seven consecutive days prior to the 8-week follow-up after discharge. A measurement day is considered valid if more than 20 hours of 24-hour mobility data are available. For each participant, mean daily step count is calculated across all available valid days within each measurement period.

Time frame
From inclusion through hospital discharge, an average of 5 days; and 7 consecutive days before the 8-week follow-up

Other outcomes

1

Self-reported mobility

Self-reported mobility by the Acute Care Mobility Assessment. A score of 0-12 can be obtained, with 0 reflecting poor mobility and 12 reflecting a high level of mobility.

Time frame
Days 2, 4 and 6 after inclusion during hospitalization
2

Life space mobility

By the Life Space Assessment-DK, which measure mobility and level of dependence in mobility. A score of 0-120 can be obtained, with 0 reflecting poor mobility and 120 reflecting high mobility

Time frame
At inclusion and 4 and 8 weeks post discharge
3

Self-reported pre-admission (2 weeks prior to admission) and post discharge mobility

By the New Mobility Score, which assesses the ability to walk indoors and outdoors and the ability to go shopping. A score from 0-9 can be obtained, with 0 reflecting low mobility and 9 reflecting high mobility.

Time frame
At inclusion and 1, 4 and 8 weeks post discharge
4

Frailty pre-admission (2 weeks prior to admission)

By the Clinical Frailty Scale, which is a clinical evaluation of the degree of frailty of a person. It is scored by health care professionals on a scale from 1 (very fit) to 9 (terminally ill)

Time frame
At inclusion

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Hvidovre University Hospital

Lead sponsor

Copenhagen University Hospital, Hvidovre

Sponsor institution

Department of Geriatric, Copenhagen University Hospital Hvidovre

Collaborator

Department of Cardiology, Copenhagen University Hospital Hvidovre

Collaborator

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