Physical Activity

149

Review clinical trials related to Physical Activity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial

This study will evaluate a program called On Track for Wellness (OTW) which is being adopted by the Illinois Department of Human Services' Division of Behavioral Health \& Recovery (DBHR) for use in all state-funded early psychosis programs in Illinois. OTW combines use of Fitbit activity trackers with health education, goal setting to promote health activation, and ongoing support for maintaining healthy lifestyles. Successful completion of this research will gauge the effectiveness of this program in improving sleep hygiene and increasing physical activity among people recently diagnosed with schizophrenia or other psychotic disorders.

Participants needed: 365
Trial details
Biological sex: AllType: InterventionalSponsor: University of Illinois at ChicagoUpdated: Oct 9, 2026Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

Multiple Sclerosis Severity and Caregiver Health Outcomes

This cross-sectional observational study aims to investigate the associations between multiple sclerosis (MS) severity and caregivers' sleep quality, physical activity, body awareness, perceived stress, and caregiver burden. A total of 68 caregivers of patients with MS will be recruited from Başkent University Hospital. MS severity will be assessed using the Expanded Disability Status Scale (EDSS), while caregiver health outcomes will be evaluated using validated questionnaires. The findings are expected to provide insight into the multidimensional impact of MS severity on caregiver health and well-being.

Participants needed: 68
Trial details
Biological sex: AllType: ObservationalSponsor: Süleyman KorkusuzUpdated: Oct 8, 2026Locations: 1
Eligibility criteria

Being 18 years of age or older. [+2]

Having a cognitive impairment that prevents completion of the assessments. [+2]

Status: Recruiting

A Multi-level Mother-daughter Physical Activity Intervention for Pre- Adolescent Latinas

The goal of this Cluster Randomized Control Trial (RCT) is to learn if the mother-daughter intervention titled "Conmigo" can increase Latina preadolescents' physical activity (PA). The main objectives of the study are: * To test the effectiveness of Conmigo on daughters' Moderate-to-Vigorous level PA (MVPA) over time * To evaluate individual (e.g. mothers' MVPA) and family level (e.g. mother-daughter communication) mechanisms of change and their bidirectional effects Researchers will compare the 10-week physical activity promotion intervention to a 10-week parallel intervention with emphasis on another health behavior (dietary intake) to see if there are differences in MVPA levels. We will enroll 216 Latina mother-daughter pairs at 18 elementary schools; each school will randomly receive the PA intervention or the control group program. Mothers and daughters will attend 10 weekly sessions (2 hours each) at their elementary school, led by YMCA staff. Informed by social cognitive theory and family systems theory, the PA intervention sessions target family-level correlates of physical activity such as PA promotion parenting strategies (monitoring, role-modeling, etc.) and mother-daughter communication. Participants in the intervention group engage in weekly PA during sessions, discuss different topics each week, and set goals and receive PA homework during the week. The investigators hypothesize that daughters participating in Conmigo will have higher minutes of device-assessed MVPA at M2 (post program), M3 (6 months post program), and M4 (12-months post program) compared to girls in the control condition.

Participants needed: 432
Trial details
Age: 8-65Biological sex: FemaleType: InterventionalSponsor: San Diego State UniversityUpdated: Oct 2, 2026Locations: 1
Eligibility criteria

Self-identifying as Latina [+8]

either Mother or Daughter has a health condition that precludes them from doing... [+2]

Status: Recruiting

Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

Strong Teens for Healthy Schools (STHS) is a school-based, civic engagement program that empowers middle school students to improve their physical activity and healthy eating behaviors, improve their cardiovascular disease outcomes, and create positive change in their school health environments.

Participants needed: 500
Trial details
Age: 8+Biological sex: AllType: InterventionalSponsor: Texas A&M UniversityUpdated: Oct 5, 2026Locations: 1
Eligibility criteria

> 50 6th and 7th grade students [+2]

6th or 7th grade student [+4]

Status: Recruiting

Effectiveness of an Intervention Combining Adapted Physical Activity and Therapeutic Education in Patients With Chronic Symptoms Attributed to Lyme Borreliosis.

Lyme borreliosis, commonly known as Lyme disease, has been clinically described for more than a century, but has been officially recognized for 40 years, with the detection of the Borrelia bacterium by W. Burgdorfer, in ticks of the Ixodes ricinus complex, identified a few years before.

Participants needed: 62
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Universitaire de Saint EtienneUpdated: Oct 2, 2026Locations: 2
Eligibility criteria

Patient referred to the reference center for tick-borne diseases by his attendin... [+3]

Patients with cardiac or respiratory pathologies that contraindicate the practic... [+2]

Status: Recruiting

Cities for Better Health Childhood Obesity Prevention Initiative in JAPAN

The goal of this interventional study is to prevent childhood obesity in children aged 6-12 years in Chiba City, Japan. The main questions it aims to answer are: * Does the multi-component intervention for environments around children reduce the BMI z-score of children aged 6-12 years after one and two years? * Does the multi-component intervention for environments around children improve the health-related quality of life (assessed by KIDSCREEN-10) of children aged 6-12 years after one and two years? Researchers will compare school clusters receiving the intervention to control clusters to see if the intervention package promotes healthy eating, increases physical activity, improves health-related quality of life, and reduces obesity prevalence. Participants will: * Attend elementary schools within participating clusters (either the intervention or control group). * Have baseline data collected, with follow-up assessments after one year and two years. * Potentially participate in school-based programs (nutrition education, physical activity promotion) and community-based initiatives (park activation, supermarkets) if in an intervention cluster. * Have their physical activity and dietary behavior assessed through self-report questionnaires.

Participants needed: 2,200
Trial details
Age: 6-12Biological sex: AllType: InterventionalSponsor: Chiba UniversityUpdated: Sep 29, 2026Locations: 1
Eligibility criteria

Children aged 6 to 12 years who are currently enrolled in one of the public elem... [+4]

Children whose parents or legal guardians fail to provide complete informed cons... [+4]

Status: Not yet recruiting

Seasonal Variation in Energy Expenditure, Water Turnover, and Physical Activity in Adults

This prospective observational study will investigate seasonal variation in total energy expenditure, water turnover, and physical activity in healthy adults living in or near Aberdeen, Scotland. Participants will complete two approximately 14-day measurement periods, one in winter and one in summer. Total energy expenditure and water turnover will be assessed using the doubly labelled water method, while physical activity and personal environmental exposure will be measured using wearable devices. The study will examine within-person differences between winter and summer and explore whether environmental factors, including ambient temperature, daylight, and sunlight exposure, are associated with changes in energy expenditure, water turnover, and physical activity.

Participants needed: 30
Trial details
Age: 18-50Biological sex: AllType: ObservationalSponsor: University of AberdeenUpdated: Oct 2, 2026Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

Prevalence and Association of Dysfunctional Breathing With Nicotine Dependence and Physical Activity Among Young Smokers

We will structure the study's summary to provide a clear and accessible overview for patients, families, and healthcare providers. The research will examine young adult cigarette smokers aged 18 to 24 to estimate the prevalence of a dysfunctional breathing-compatible symptom pattern using the Nijmegen Questionnaire. Furthermore, the study will assess how nicotine dependence severity-measured via the Fagerström Test for Nicotine Dependence-and physical activity levels-assessed using the International Physical Activity Questionnaire-relate to this symptom burden. We will recruit participants through social media announcements and conduct face-to-face evaluations at Istinye University. The project will employ hierarchical linear and binary logistic regression models, adjusting for age, sex, and body mass index, to determine independent predictors of dysfunctional breathing. Ultimately, the findings will provide valuable insights into the combined impacts of smoking severity and physical activity on respiratory health in young adults.

Participants needed: 420
Trial details
Age: 18-24Biological sex: AllType: ObservationalSponsor: Istinye UniversityUpdated: Sep 28, 2026
Eligibility criteria

Being between 18 and 24 years of age. [+1]

Having a diagnosed personality disorder. [+3]

Status: Not yet recruiting

Physical Activity in Lawyers: Factors Affecting Musculoskeletal Pain

This study aims to determine the prevalence and distribution of musculoskeletal pain among lawyers registered with the Isparta Bar Association, specifically in relation to their varying levels of physical activity. The data obtained will help establish the relationships between physical activity levels, occupational factors, stress, and job satisfaction, thereby providing a foundation for developing personalized and preventive physiotherapy approaches for this specific population. Furthermore, the study will serve as a guiding resource for the ergonomic improvement of lawyers' working conditions and the formulation of occupational health policies. H1: There is a statistically significant relationship between lawyers' physical activity levels and the frequency, distribution, and severity of musculoskeletal pain in various anatomical regions of the body. H2: Physical activity level, perceived stress, occupational burnout, and job satisfaction levels are significant predictors of musculoskeletal pain among lawyers. H3: There is a statistically significant difference between lawyers' sociodemographic and professional characteristics (duration of employment, daily time spent at a desk and using a computer, etc.) and their perceived stress and job satisfaction scores. H4: Musculoskeletal complaints and functional limitations are significantly higher among lawyers experiencing high levels of perceived stress and occupational burnout compared to the group reporting low stress and burnout.

Participants needed: 102
Trial details
Age: 25-65Biological sex: AllType: ObservationalSponsor: Suleyman Demirel UniversityUpdated: Sep 24, 2026Duration: 1 Day
Eligibility criteria

Not listed

Status: Not yet recruiting

Impact of Adolescence Body Image on Body Functionality and Physical Activity

This cross-sectional study will investigate how Egyptian adolescents aged 14-17 years perceive their bodies and how these perceptions are related to body functionality and physical activity. The study will examine different patterns of body image concerns, including high, moderate, and low concern, and explore whether these patterns are associated with how adolescents appreciate what their bodies can do and how physically active they are. Participants will complete questionnaires assessing body shape concerns, body appreciation and functionality, and physical activity. The study aims to improve understanding of the relationship between body image, body functionality, and physical activity during adolescence and may provide useful information for healthcare professionals, particularly physical therapists, when developing strategies to promote physical activity and overall well-being among adolescents.

Participants needed: 385
Trial details
Age: 14-18Biological sex: AllType: ObservationalSponsor: Sinai UniversityUpdated: Sep 25, 2026
Eligibility criteria

Not listed

Status: Not yet recruiting

Physical Activity During Hospitalization and Hospital-Associated Disability

This study examines physical activity during and after hospitalization in acutely hospitalized older adults and its association with hospital-associated disability (HAD). Older adults have low levels of physical activity during acute hospitalization, which is associated with an increased risk of HAD. HAD is a decline in the ability to perform activities of daily living that occurs in relation to hospitalization and cannot be explained by the acute illness alone. HAD affects up to 30% of acutely hospitalized older adults and is associated with adverse outcomes, including an increased risk of discharge to a nursing home, readmission, and mortality. Furthermore, patients who develop HAD are at risk of not regaining their pre-admission functional level and experiencing persistent functional decline after discharge. Physical activity and exercise are recommended as strategies to prevent HAD. However, many acutely hospitalized older adults have limited capacity or motivation to engage in structured exercise. It therefore remains unclear how much physical activity during hospitalization is sufficient to reduce the risk of HAD and which types of physical activity patients are able and prefer to perform. The study will also examine patients' ability and preferences for different types of physical activity during hospitalization and explore their motivation, barriers, and preferences for physical activity after discharge. The results may help identify clinically relevant levels of physical activity during hospitalization and contribute to more patient-centered approaches to supporting physical activity and preventing functional decline during and after hospitalization.

Participants needed: 170
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Hvidovre University HospitalUpdated: Sep 21, 2026Locations: 1
Eligibility criteria

Aged 65 years or older [+1]

In isolation [+4]

Status: Not yet recruiting

REmote Physical ACtivity Intervention for High Blood Pressure Postpartum

The purpose of this intervention is to help new mothers who had elevated blood pressure during pregnancy become more physically active after birth. The investigators will connect data from FitBits to the electronic health record. Women will then get weekly messages with feedback and goals to help them stay active. The investigators will test if the intervention improves step counts and blood pressure after pregnancy. The investigators will also test if the intervention is feasible and enjoyed by postpartum women.

Participants needed: 60
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Northwestern UniversityUpdated: Sep 17, 2026
Eligibility criteria

Delivery of a live birth at Northwestern Medicine 6-12 weeks prior [+6]

Medical contraindications to participating in a structured physical activity pro... [+2]

Status: Not yet recruiting

Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children

Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders. However, there is a lack of longitudinal research investigating the developmental processes contributing to loss of control eating in youth. While physical activity, sedentary behavior, and self-regulation have been linked to the regulation of eating, no research has examined the mechanistic processes by which these domains may together impact loss of control eating during childhood and adolescence. Furthermore, given that these factors (i.e., activity, self-regulation, and eating behavior) vary considerably from moment-to-moment, it is imperative to utilize methodology that can capture momentary, real-time fluctuations in these domains. Therefore, the current study proposes to use a biobehavioral, multi-method approach integrating neuroimaging, accelerometry, neurocognitive assessments, and ecological momentary assessment (EMA) to study how physical activity and sedentary behavior patterns and self-regulation influence loss of control eating and related eating disorder psychopathology from late childhood to adolescence, which is a critical transitional developmental period. Male and female children aged 10-12 at baseline (N=200) will be recruited to complete annual assessments for 3 years. Aim 1 (momentary) - Examine momentary associations between physical activity patterns, self-regulatory mechanisms (i.e., inhibitory control, emotion functioning, and food-related reward anticipation) and loss of control eating in daily life using multi-method ambulatory assessment. Hypothesis 1a: Momentary decreases in physical activity and increases in sedentary behavior, compared to one's usual level, will be associated with increases in loss of control eating. Hypothesis 1b: Momentary decreases in self-regulatory mechanisms (i.e., decreases in inhibitory control, emotion regulation, and positive affect, and increases in negative affect and food-related reward anticipation) will explain (i.e., mediate) associations between decreases in physical activity/increases in sedentary behavior and subsequent increases in loss of control eating. Aim 2 (longitudinal) - Examine longitudinal associations between physical activity patterns, self-regulatory mechanisms, and binge eating and related eating pathology (i.e., loss of control eating, binge episodes, eating disorder onset, global eating psychopathology) using multimethod ambulatory assessment and functional magnetic resonance imaging (fMRI). Hypothesis 2: Across a three-year follow-up, children who show greater decreases in physical activity and increases in sedentary behavior, compared to other children, will demonstrate greater decreases in self-regulatory capacity (i.e., decreases in inhibitory control, emotion regulation, and positive affect, and increases in negative affect and food-related reward anticipation), which in turn will predict increases in binge eating and related eating pathology by year three. The hypothesis will be evaluated using self-regulation indices measured via EMA (Hypothesis 2a) and via task-evoked neural activations during fMRI (Hypothesis 2b).

Participants needed: 200
Trial details
Age: 10-12Biological sex: AllType: InterventionalSponsor: The University of Texas at DallasUpdated: Sep 16, 2026Locations: 3
Eligibility criteria

Can read and speak English. [+1]

Diagnosis of an eating disorder other than binge-eating disorder or subthreshold... [+8]

Status: Not yet recruiting

Project GAME ON! A Digital Comic Tool to Promote Healthy Behaviors

This clinical trial aims to evaluate an interactive, culturally relevant digital health promotion comic designed to support healthy dietary and physical activity behaviors among Black/African American and Latino children ages 8 to 12 years. The comic allows children's choices to affect the storyline and health content, with the goal of increasing engagement, empowering children, and improving attitudes, beliefs, and self-efficacy related to healthy behaviors. Caregivers will also receive newsletters reinforcing healthy dietary and physical activity behaviors at home. The main questions it aims to answer are: 1. Does an interactive, customizable "choose-your-own-adventure" style comic lead to greater engagement and acceptability compared to standard digital comic formats? 2. Is greater engagement with the comic associated with improved self-efficacy related to dietary and physical activity behaviors? Researchers will compare three study groups to evaluate differences in engagement, acceptability, and self-efficacy outcomes related to dietary and physical activity behaviors. Participants will: * Use a 6-week digital comic and health promotion website remotely * Complete surveys about engagement, attitudes, beliefs, and self-efficacy related to healthy behaviors * Receive periodic reminders and support messages during the intervention period * For caregivers in the enhanced and non-enhanced comic groups: receive newsletters promoting healthy dietary and physical activity behaviors at home

Participants needed: 180
Trial details
Age: 8-12Biological sex: AllType: InterventionalSponsor: Tufts UniversityUpdated: Sep 15, 2026
Eligibility criteria

Self-identifies as Black/AA and/or Latino [+19]

has allergies, food aversions, food disorders, or medications with side-effects... [+2]

Status: Recruiting

An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

The goal of this feasibility randomized controlled trial is to assess the feasibility, acceptability, and demand, as well as preliminary effects of an evidence-based Intuitive Eating (IE) intervention among pregnant women who have obesity. The main research questions are: RQ1: What is the feasibility (acceptability and demand) of implementing an Intuitive Eating Intervention among pregnant and postpartum women? RQ2: How does participation in the Pregnancy Intuitive Eating Intervention (PIE-I) impact key maternal health outcomes (i.e., gestational weight gain, intuitive eating behaviors, dietary quality, body image, and mental health) compared to a wait-list control? Researchers will compare the Pregnancy Intuitive Eating Intervention (PIE-I) intervention group with the wait-list control to see what impact the PIE-I has on maternal well-being. Participants randomized to the intervention group will complete the 8 week asynchronous IE intervention and have an opportunity to interview at the end of the study.

Participants needed: 80
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: San Diego State UniversityUpdated: Sep 15, 2026Locations: 2
Eligibility criteria

Age ≥18 years [+5]

Current or past diagnosis of an eating disorder (e.g., anorexia nervosa, bulimia... [+5]

Status: Not yet recruiting

Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities

The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes. We will also assess the impact of the program on residents' physical activity and function.

Participants needed: 344
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Maryland, BaltimoreUpdated: Aug 25, 2026Locations: 1
Eligibility criteria

18 years of age or older [+3]

do not pass the Evaluation to Sign Consent test [+5]

Status: Recruiting

Evaluation of Choose to Move Replacement Ready (CTM-RR)

Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada. Recently, the investigators adapted CTM for the \>14000 people in BC who are on surgical waitlists for total knee replacement or total hip replacement (TKR/THR) for osteoarthritis (OA). The primary goals of this observational study are to describe how the adapted program, Choose to Move Replacement Ready (CTM-RR), is implemented in BC and determine if the adapted program improves health outcomes in people with hip and/or knee osteoarthritis who are on surgical waitlists for TKR/THR. The investigators will also evaluate whether any health benefits achieved by CTM-RR participants are maintained three months after they finish the program and also during the remaining time that they wait for their TKR/THR surgery. The investigators will work with referral partners from hospitals and orthopaedic clinics in BC to recruit participants into CTM-RR. Participants who enrol in CTM-RR will answer online survey questions about the program and about their physical activity, mobility, pain, function, quality of life, willingness to undergo surgery, overall perception of their joint condition, psychosocial health, self-efficacy, social isolation, loneliness, and sedentary time. CTM-RR activity coaches will also answer online survey questions about the program. CTM-RR participants, activity coaches, and referral partners will also participate in interviews about the program.

Participants needed: 210
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of British ColumbiaUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

Activity coach hired by the Active Aging Society (activity coaches must speak En... [+2]

non-English speaking activity coach [+1]

Status: Recruiting

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

The AYA WELL study is a 2-arm randomized clinical trial to test the efficacy of a theory-based, mHealth weight management intervention adapted specifically for adolescent and young adult cancer survivors compared to a self-guided arm. Participants, diagnosed with cancer between ages 15-39, currently age 18-39, post-treatment at least 6 months, and who have overweight or obesity will be randomized to receive either: 1) a comprehensive mHealth weight management program (intervention) or 2) digital tools + health education + peer support (self-guided) over 12 months. Outcomes will be assessed at 3, 6, and 12 months.

Participants needed: 240
Trial details
Age: 18-39Biological sex: AllType: InterventionalSponsor: UNC Lineberger Comprehensive Cancer CenterUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

18-39 years old at the time of consent. [+4]

Type 1 diabetes or currently receiving certain medical treatments for Type 2 dia... [+17]

Status: Not yet recruiting

Self-directed Use of Resources for Physical Activity

This is a pilot RCT examining physical activity outcomes at 3 months across 3 conditions: use of large language model (LLM) fully self-directed; use of LLM with guidance; and use of online tools to help with sleep.

Participants needed: 39
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: University of FloridaUpdated: Aug 21, 2026
Eligibility criteria

Age 18-75 [+4]

Any history of MI or stroke, arrhythmias, or heart failure [+15]

Status: Recruiting

AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in self-determination theory (SDT) and behavioral change techniques (BCTs) among older adults. As no data exists on the feasibility of AI-driven exercise programs grounded in SDT and multiple BCTs specifically for older adults, this will be a pioneering study to explore the feasibility of wearable and AI-driven exercise program protocols and the rates of acceptance and appropriateness of the exercise prescription intervention among older adults. In addition, this study will test the preliminary efficacy of the intervention on physical activity (PA), mental health, and quality of life. This study follows the National Institute of Health (NIH) stage model, and it represents stage 1b of the NIH stage model, which emphasizes the feasibility and actionable processes for delivering a new health intervention. Specifically, this study will: 1.Evaluate the research protocol feasibility of a wearable and AI-driven mobile application-based exercise prescription grounded in SDT and BCTs (of goal setting, self-monitoring, graded task, and demonstration) on older adults over 8 weeks 2. Evaluate the acceptability and appropriateness of a wearable, AI-driven, mobile application-based exercise prescription grounded in SDT and BCTs among older adults over 8 weeks. 3. Evaluate the preliminary impact of a wearable and AI-driven mobile application-based exercise prescription grounded in SDT and BCTs on older adult PA (steps per day and daily duration of light PA and Moderate-vigorous PA), sedentary time, sleep, mental health (depression and anxiety), and quality of life.

Participants needed: 20
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: The University of Tennessee, KnoxvilleUpdated: Aug 20, 2026Locations: 1
Eligibility criteria

Be aged 65 years or older. [+6]

Are younger than 65 years of age. [+5]

Status: Recruiting

Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan

Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day. This is called a sedentary lifestyle, and it increases the risk of heart diseases. This research project aims to find out if a newly developed context specific mobile phone application can help these sedentary employees to improve their lifestyle. The app, called m-LIfE (mHealth-based Lifestyle Intervention for Employees), will be designed to help employees to move more during the day and eat healthier food like fruits and vegetables. The study will involve bank employees in urban Karachi, Pakistan. They will be divided into two arms: Intervention arm: Participants in this arm will use the m-LIfE app for 12 weeks. They will get reminders and tips to take breaks, exercise, and eat healthy. Routine care arm: Participants in this arm will receive printed basic educational material about prevention of risk factors of heart diseases and improving lifestyle. After the 12 weeks of intervention, there will be a follow-up period at 4th week to check if participants are maintaining healthy habits. This study could help find simple and affordable ways to improve the health of office workers and reduce pressure on the healthcare system.

Participants needed: 84
Trial details
Age: 20-65Biological sex: AllType: InterventionalSponsor: Aga Khan UniversityUpdated: Aug 12, 2026Locations: 1
Eligibility criteria

Diagnosed case of myocardial infarction, stroke, coronary heart disease, cerebro... [+2]

Status: Not yet recruiting

Effectiveness of NeoMayor in Improving Cardiovascular Health in Chilean Older Adults

This study aims to evaluate the effectiveness of NeoMayor, a mobile health (mHealth) intervention designed to improve cardiovascular health among older adults at elevated cardiovascular risk in Chile. NeoMayor is a smartphone-based application that provides personalized guidance on physical activity, diet, sleep, and mental well-being through a multidomain lifestyle approach. This multicenter randomized controlled trial will enroll community-dwelling older adults aged 55 to 75 years recruited from primary healthcare centers in urban and rural settings. Participants will be randomized in a 2:1 ratio to either the NeoMayor intervention or a control group receiving standard health information and usual care. The intervention duration will be four months. The primary objective is to determine whether the NeoMayor intervention improves cardiovascular health as measured by the Life's Essential 8 Cardiovascular Health Index. Secondary objectives include evaluating changes in cognitive performance, depressive symptoms, anxiety symptoms, quality of life and physical performance outcomes. The study will also assess feasibility and adherence to digital intervention.

Participants needed: 240
Trial details
Age: 55-75Biological sex: AllType: InterventionalSponsor: University of ChileUpdated: Aug 10, 2026Locations: 2
Eligibility criteria

Age between 55 and 75 years [+4]

Dementia defined as a score in the MEFO < 9 [+5]

Status: Recruiting

The eHealth Integrated Maternal Physical Activity Programme in Prenatal Care Trial (E-IMPACT)

This will be a proof-of-concept randomised control trial (RCT) study, where 100 pregnant women will be recruited in the first trimester of pregnancy and followed-up until delivery. It aims to test these following hypotheses: 1. pregnancy is a window of opportunity to implement good lifestyle habits of physical activity and exercise as pregnant women are in regular contact with health professionals and are likely motivated and be more confident to carry out these activities according to the guidelines 2. this integrated programme will effective in a healthcare setting, and will bring Singapore's "Guidelines on Physical Activity and Exercise in Pregnancy" guidelines to implementation 3. with enhanced self-efficacy and motivation, the proportion of women engaging in adequate physical activity during pregnancy will increase to meet recommended guidelines.

Participants needed: 100
Trial details
Age: 21-45Biological sex: FemaleType: InterventionalSponsor: KK Women's and Children's HospitalUpdated: Aug 10, 2026Locations: 1
Eligibility criteria

Pregnant women (First trimester at least 4 weeks gestation) [+4]

Women who have severe chronic disease such as chronic kidney disease, hypertensi... [+3]

Status: Not yet recruiting

POSH-Ex: Physiotherapist-Led Telerehabilitation Exercise Programme for Postpartum Sexual Health

Postpartum women frequently experience impairments in sexual function, pelvic floor dysfunction, fatigue, and depressive symptoms, all of which may adversely affect their quality of life during the postpartum period. Although pelvic floor muscle training is recommended as part of postpartum rehabilitation, evidence regarding comprehensive physiotherapist-led exercise programmes specifically targeting postpartum sexual health remains limited. Furthermore, no standardized telerehabilitation programme has yet been evaluated using a randomized controlled trial design. The aim of this randomized controlled trial is to evaluate the effectiveness of the POSH-Ex (Postpartum Sexual Health Exercise) programme, a standardized 12-week physiotherapist-led telerehabilitation intervention designed to improve female sexual function and overall postpartum health after childbirth. Secondary objectives are to evaluate its effects on pelvic floor muscle strength, physical activity, fatigue, depressive symptoms, health-related quality of life, and body composition. A total of 84 postpartum women will be randomly allocated in a 1:1 ratio to either the intervention group or the control group. Participants in the intervention group will complete supervised online exercise sessions twice weekly for 12 weeks, while participants in the control group will receive usual postpartum care. Outcome assessments will be performed at baseline and immediately after completion of the intervention. The primary outcome is female sexual function assessed using the Female Sexual Function Index (FSFI). Secondary outcomes include pelvic floor muscle strength, physical activity, fatigue, depressive symptoms, health-related quality of life, and body composition. The findings are expected to provide high-quality evidence regarding the effectiveness of a standardized telerehabilitation programme for postpartum rehabilitation and may contribute to the development of evidence-based postpartum rehabilitation programmes and future clinical practice guidelines.

Participants needed: 84
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: University Medical Centre LjubljanaUpdated: Aug 5, 2026Locations: 1
Eligibility criteria

Women aged 18 to 45 years. [+7]

• Medical contraindications to exercise according to current clinical recommenda... [+6]

Status: Not yet recruiting

Digitalized Exercise Fit Tool Intervention for Adolescents With Blood Cancer

The goal of this clinical trial is to learn if a digitalised Exercise Fit Tool (EFT) mobile application can promote physical activity in adolescents aged 12-18 years who have completed treatment for hematologic cancer (e.g., leukaemia and lymphoma). The main questions it aims to answer are: 1. Is it feasible to conduct a larger randomised controlled trial of the digitalised EFT intervention? 2. Does the digitalised EFT intervention improve physical activity levels, physical activity self-efficacy, and quality of life at 6 months? Researchers will compare the digitalised EFT intervention group to a usual care group to see if the mobile application can promote physical activity levels, physical activity self-efficacy, and quality of life in adolescents with hematologic cancer.Participants will: 1. Receive a 20-minute educational session on how to use the mobile application 2. Use the mobile application to self-assess their appropriate physical activity level and exercise with a virtual coach 3. Complete questionnaires and wear an accelerometer at 1, 3, and 6 months after enrollment 4. Attend a 20-30-minute individual interview at 6 months (intervention group only, 10 participants)

Participants needed: 30
Trial details
Age: 12-18Biological sex: AllType: InterventionalSponsor: The Hong Kong Polytechnic UniversityUpdated: Jul 27, 2026
Eligibility criteria

(1) they are 12-18 years old; [+4]

(1) Receiving palliative care [+2]