Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-35
SponsorAssiut University

About this trial

Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index \[BMI\] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical site infections, fluid collections (seroma/hematoma), and wound separation. Postoperative wound dressings protect the surgical incision, but the optimal timing for dressing removal remains uncertain, particularly for high-risk patients.

The purpose of this prospective cohort study is to compare wound healing and the occurrence of surgical site infections between two standard dressing removal schedules in women with a BMI ≥ 30 kg/m² undergoing cesarean delivery.

Participants are observed in one of two groups according to standard hospital practice:

* Group 1: The sterile wound dressing is removed at approximately 48 hours after surgery. * Group 2: The sterile wound dressing is removed at approximately 5 days after surgery.

Following dressing removal, incisions are assessed for signs of infection, drainage, swelling, and healing progress. The study aims to provide evidence on whether earlier dressing removal at 48 hours is safe and effective compared to delayed removal at 5 days in women with obesity.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Women aged 18 to 35 years

Body mass index (BMI) ≥ 30 kg/m² measured before cesarean delivery or at admission

Undergoing cesarean delivery with a Pfannenstiel skin incision and primary skin closure

Disqualifiers

Pre-existing infection or inflammation at the planned incision site

Active systemic infection or fever prior to surgery

Clinical or subclinical chorioamnionitis

Major intraoperative contamination of the surgical field

Trial population

Pregnant women aged 18 to 35 years with a body mass index (BMI) ≥ 30 kg/m² undergoing cesarean delivery via a Pfannenstiel skin incision at the Department of Obstetrics and Gynecology, Assiut University Hospitals, and Malawi Specialized Hospital.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

726 Participants
are grouped into 2 trial groups
Group A: 48-Hour Dressing Removal
Group B: 5-Day Dressing Removal

Trial outcomes

Primary outcomes

1

Number of Participants With Surgical Site Infection (SSI)

Number of participants diagnosed with a surgical site infection (SSI) at the Pfannenstiel incision site. Assessment is performed using a standardized clinical wound-assessment form evaluating the presence of purulent discharge, localized erythema, heat, edema, or wound separation.

Time frame
Up to 48 hours after dressing removal

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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