Unilateral Spinal Anesthesia vs Popliteal-Adductor Canal Block for Below-knee Amputation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-70
SponsorSargodha Medical College

About this trial

To compare the mean duration of postoperative analgesia between unilateral spinal anaesthesia and combined popliteal sciatic nerve block with adductor canal block in diabetic patients undergoing below-knee amputation.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged 40 to 75 years, of either gender.

Known type 2 diabetes mellitus scheduled for below-knee amputation.

ASA physical status II or III.

Disqualifiers

Documented allergy to amide local anaesthetics.

A bleeding tendency, or the use of anticoagulant or antiplatelet drugs, makes regional anaesthesia unsafe.

Skin infection at the spinal or block puncture site.

Pre-existing nerve disease of the same limb that would confuse block assessment.

Trial design

Design model

Parallel

Treatments tested in this trial

  • 0.5 % hyperbaric Bupvicaine

    Drug

    Patients in Group A will receive unilateral spinal anaesthesia. The anesthesiologist will inject a small dose of 0.5% hyperbaric bupivacaine through a pencil-point spinal needle, keep the limb to be operated on in the dependent position, and hold the lateral posture for about fifteen minutes so the block settles on one side. Patients in Group B will receive an ultrasound-guided popliteal sciatic nerve block together wi

  • 15 ml of 0.5 bupvicaine

    Drug

    Group B will receive 15 mL of 0.5% bupivacaine for the popliteal sciatic nerve block and 10 mL of 0.25% bupivacaine for the adductor canal block (total 25 mL), keeping the total dose within 2 mg/kg

Treatment groups

68 Participants
are divided into 2 treatment groups
Group A: Unilateral spinal anesthesiaOther 1 intervention
Group B: Combination popliteal and adductor canal nerve blockOther 1 intervention

Trial outcomes

Primary outcomes

1

Postoperative analgesia

This will be assessed by visual analogue scale

Time frame
24 hours
2

Total analgesic consumption

Time frame
24 hours

Secondary outcomes

1

Complication

Complication such as vascular puncture and Local anesthetic systemic toxicity

Time frame
With in 24 hours
2

Hemodynamics variable

Variable such as Heart rate, Blood pressure

Time frame
With in 24 hours

Other outcomes

Sponsors and contacts

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