Clinical trials

To compare the mean onset of sensory block and mean time to first rescue analgesia between ropivacaine with dexmedetomidine and ropivacaine with tramadol in ultrasound-guided pericapsular nerve group block for postoperative analgesia in patients undergoing hip surgeries.

To compare the mean duration of postoperative analgesia between unilateral spinal anaesthesia and combined popliteal sciatic nerve block with adductor canal block in diabetic patients undergoing below-knee amputation.

Neonatal asphyxia causes significant global morbidity, frequently resulting in Hypoxic-Ischemic Encephalopathy (HIE). In resource-limited settings where therapeutic hypothermia is unavailable, affordable neuroprotective options are needed. Intravenous magnesium sulphate blocks NMDA receptors, limiting cellular calcium influx and neuroinflammation. This randomized controlled trial evaluates whether adjuvant intravenous magnesium sulphate (250\\text{ mg/kg} within 6 hours of birth) reduces the duration of hospital stay and improves short-term clinical outcomes in term neonates with birth asphyxia.