Impacted Mandibular Third Molar

3

Review clinical trials related to Impacted Mandibular Third Molar. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars

This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars. The study will evaluate postoperative pain, intraoperative blood loss, and wound healing in patients undergoing third molar surgery. A total of 78 participants will be randomly allocated in a 1:1 ratio to receive either a scalpel blade incision or an electrocautery incision under standardized surgical conditions.

Participants needed: 78
Trial details
Age: 15-65Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Jul 23, 2026Locations: 1
Eligibility criteria

Male and female patients. [+3]

* Patients with uncontrolled systemic disease or immuno-compromised status. [+6]

Status: Recruiting

The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery

1\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.

Participants needed: 148
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Recep Tayyip Erdogan UniversityUpdated: Jun 9, 2026Locations: 1
Eligibility criteria

Patients aged 18-40 years. [+2]

Patients classified as ASA II, III, or IV. [+9]

Status: Not yet recruiting

"Effect of Preoperative Submucosal Dexamethasone on Postoperative Discomfort After Mandibular Third Molar Surgery"

This study aims to determine whether giving a single dose of dexamethasone before surgery can reduce pain and difficulty in opening the mouth after removal of an impacted lower wisdom tooth. Pain and limited mouth opening are common problems after this procedure and can affect eating, speaking, and daily activities. A total of 268 patients aged 18 to 55 years who require surgical removal of an impacted mandibular third molar will be included. Participants will be randomly assigned to one of two groups. One group will receive a 4 mg dexamethasone injection under the gum before surgery, while the other group will not receive this medication. All patients will undergo the same surgical procedure and receive standard postoperative care. Pain will be measured using a visual analogue scale, and mouth opening will be assessed using a standard measuring method. These outcomes will be recorded on the second and seventh days after surgery. The results of this study will help determine whether preoperative dexamethasone is an effective and simple method to reduce postoperative discomfort and improve recovery after third molar surgery.

Participants needed: 268
Trial details
Phase: Phase 4Age: 18-55Biological sex: AllType: InterventionalSponsor: Hayat Abad Medical Complex, PeshawarUpdated: May 1, 2026
Eligibility criteria

Adults aged 18 to 55 years [+2]

Patients with systemic diseases [+4]