Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Contact Radiotherapy for Rectal Cancer

The aim of the CORRECT phase 2 study is to show non-inferiority of Contact x-ray brachytherapy (CXB) + short-course radiotherapy (SCRT) compared to the experimental arm of the OPERA trial in organ preservation for early and early intermediate rectal cancer (cT1-3abN1).

Participants needed: 110
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Alexander ValdmanUpdated: Aug 10, 2026Locations: 2
Eligibility criteria

cT1-cT3ab, < 5 cm largest diameter and < ½ circumference (MRI staging), N0-N1 (<... [+7]

Inoperable patient [+15]

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Status: Recruiting

Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT)

To investigate a potential toxicity benefit of preoperative radiation therapy with protons compared to conventional photon beam radiation therapy in patients with locally advanced rectal cancer.

Participants needed: 254
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Alexander ValdmanUpdated: Aug 10, 2026Locations: 9
Eligibility criteria

Biopsy-proven, newly diagnosed primary rectal adenocarcinoma, i.e. with the lowe... [+16]

Extensive growth into cranial part of the sacrum (above S3) or the lumbosacral n... [+13]

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