Burnout

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Review clinical trials related to Burnout. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents

The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia, and depression as well as to determine the feasibility and acceptability of the meditation practice by Weill Cornell employees. The main question the study aims to answer is whether: • Levels of burnout, anxiety, insomnia, and depression will be decreased, and overall mental well-being will improve over a 3.5-month period before and after TM intervention. Participants will attend 9 sessions total (8 group sessions and 1 individual session) with a certified TM instructor from The David Lynch Foundation Institute for Mental Health and Resilience where they will gain experience in proper TM techniques. Also, participants will conduct 2 of their own TM sessions at home daily during the course of this study.

Participants needed: 15
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Weill Medical College of Cornell UniversityUpdated: Oct 9, 2026Locations: 1
Eligibility criteria

Be 18 years of age or older [+5]

Are younger than 18 years of age. [+7]

Status: Not yet recruiting

Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems

Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout. Hand in Hand is a four-week, self-guided, compassion-focused app developed to support parents of children and adolescents referred to Child and Adolescent Mental Health Services (CAMHS). Drawing on principles from Compassion Focused Therapy (CFT) and inspired by work by Kirby et al., the app was developed through a participatory co-design process involving parents and clinical and research experts. The project comprises two interrelated sub-studies. Sub-study 1 is an open feasibility study evaluating the feasibility and preliminary outcomes of Hand in Hand among parents of children and adolescents referred to CAMHS in the Central Denmark Region. Feasibility outcomes include recruitment, retention, adherence, engagement, acceptability, and data completeness. Preliminary changes in parental outcomes, including parental burnout, emotion regulation, family empowerment, self-compassion, self-criticism, shame, and emotional distress, as well as parent-reported child outcomes, will also be explored. Sub-study 2 is an embedded qualitative study exploring parents' experiences of using Hand in Hand and their perceptions of whether and how the intervention influences parental well-being and family interactions.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of AarhusUpdated: Sep 25, 2026
Eligibility criteria

Parents of a child or adolescent referred to CAMHS in Central Denmark Region (el... [+4]

No specific exclusion criteria

Status: Not yet recruiting

Effects of a Connection-Enhancement Program for Newly Employed Generation Z Nurses.

The purpose of this randomized controlled trial is to evaluate the effects of a connection-enhancement program on resilience, perceived stress, burnout, and intention to stay among newly employed Generation Z nurses in a military hospital. Approximately 80 eligible nurses will be randomly assigned to either an intervention group or a control group. The control group will receive conventional orientation education for newly employed nurses, whereas the intervention group will receive the connection-enhancement program in addition to conventional orientation education. The intervention will be delivered over four weeks, with one 50-60-minute session per week. Outcomes will be assessed before and after the intervention using self-reported questionnaires and salivary cortisol measurements.

Participants needed: 80
Trial details
Age: 20-29Biological sex: AllType: InterventionalSponsor: National Defense Medical University, TaiwanUpdated: Sep 22, 2026
Eligibility criteria

Newly employed nurses who are currently working at Tri-Service General Hospital... [+3]

Born before 1997 [+2]

Status: Recruiting

Psilocybin-Assisted Therapy for Physician Well-Being and Burnout

Through an open-label study involving a small group of UCSD physicians experiencing burnout, the investigators will evaluate the feasibility, safety, and preliminary effectiveness of PAT to reduce burnout symptoms.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Age: 21-70Biological sex: AllType: InterventionalSponsor: University of California, San DiegoUpdated: Sep 2, 2026Locations: 1
Eligibility criteria

Faculty physician, aged 21-70. Volunteer faculty are not included [+5]

Previous inpatient psychiatric hospitalization(s) [+11]

Status: Recruiting

Evaluation of Speech and Voice Biomarkers in Association With Burnout

This project aims to explore how speech patterns and voice characteristics can be used to detect signs of burnout and stress in physicians.

Participants needed: 200
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Minneapolis Heart Institute FoundationUpdated: Aug 24, 2026Locations: 1
Eligibility criteria

Adult individuals (18 years-old or older) [+7]

English is not their preferred language [+13]

Status: Recruiting

Evidence-Based Quality Improvement to Reduce VA Primary Care Burnout

Burnout is highly prevalent among VA primary care providers and staff, impairing productivity and retention, as well as safety, quality, and patient experience. In this pilot trial, the investigators will facilitate the development of burnout reduction interventions using an evidence-based quality improvement (EBQI) approach, and then evaluate the feasibility, acceptability and effectiveness of a pilot EBQI-facilitated burnout reduction intervention in a modified stepped wedge design in one VA region.

Participants needed: 203
Trial details
Biological sex: AllType: InterventionalSponsor: VA Greater Los Angeles Healthcare SystemUpdated: Aug 19, 2026Locations: 5
Eligibility criteria

5 primary care clinics (2 VA Medical Centers [VAMCs] and 3 community-based outpa... [+1]

All other VAMCs and CBOCs. [+2]

Status: Recruiting

Mindfulness-based Relapse Prevention for Peer Workers

Adapt and test the effectiveness of MBRP for substance use peer workers compared to a standard of care (referral to 12-step) control condition on substance use, relapse risk, and burnout among peers in a pilot hybrid type 1 trial. The goal of this clinical trial is to learn if Mindfulness-Based Relapse Prevention can reduce substance use, relapse risk, and burnout among substance use peer workers. The objectives are to: 1. Identify the causes, consequences, and risk and protective factors for relapse among peer workers; 2. Identify peers' preferences related to MBRP content, structure, and delivery; 3. Adapt the MBRP intervention for peer workers; and 4. Assess the preliminary effectiveness and implementation outcomes of the adapted MBRP intervention. Researchers will compare MBRP to referral to 12-step (standard of care) to see if MRBP works to reduce substance use, relapse risk, and burnout. Participants will asked to: * Participate in MBRP (8 weekly 2-hour virtual sessions) * Complete 4 surveys assessing well-being outcomes * Participate in 1 virtual interview about your experience

Participants needed: 80
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: University of Texas at AustinUpdated: Aug 7, 2026Locations: 1
Eligibility criteria

Are > 18 years old [+3]

Have a cognitive impairment that jeopardizes informed consent [+1]

Status: Recruiting

Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs)

This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of the Dutch adaptation of an in-person group intervention for workplace supervisors - Advancing Supervisors' Capacity for Mental Health at Work (ASCEND) - in Dutch Small and Medium-sized Enterprises (SMEs). The ASCEND intervention is designed to equip supervisors with the skills to: i) know when to support their workers; ii) how to direct workers to support, and iii) advocate for action on mental health at work. The primary objectives of this project are to: * Assess to what extent the Dutch adaptation of the WHO-developed ASCEND intervention is effective in enhancing supervisors' confidence, responsiveness, mental health literacy, and self-care practices, and in reducing supervisor stigma towards mental health conditions within Dutch SMEs. * Evaluate the impact of the ASCEND intervention on employee outcomes, including mental health and work-related outcomes among supervisees (i.e., subordinates), as well as overall organizational absenteeism rates. * Identify barriers, facilitators, and key implementation and adoption indicators to support future opportunities for scaling up the ASCEND intervention. Researchers will compare two groups to evaluate the effectiveness of the ASCEND intervention. One group will receive the training (the intervention group), while the other group will receive the training after the final follow-up period (the control group). Data will be collected from both supervisors and their supervisees (i.e., subordinates) via online questionnaires at various time points. In addition, general organizational information, including absenteeism rates, will be gathered through a representative from each participating organization. To further explore the feasibility of scaling up the ASCEND intervention within the Netherlands, qualitative data will be collected through interviews and/or focus group discussions.

Participants needed: 148
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: VU University of AmsterdamUpdated: Jul 21, 2026Locations: 1
Eligibility criteria

Having 10 to 250 employees [+10]

Status: Recruiting

FLOAT for Healthcare PTSS

This early-stage pilot trial aims to examine the feasibility, tolerability, and safety of Floatation-REST, or Reduced Environmental Stimulation Therapy via floatation in frontline healthcare workers, first responders, and emergency medical personnel who experience post-traumatic stress symptoms.

Participants needed: 15
Trial details
Phase: Early Phase 1Age: 18-64Biological sex: AllType: InterventionalSponsor: Laureate Institute for Brain Research, Inc.Updated: Jul 17, 2026Locations: 1
Eligibility criteria

First responder or other emergency medical personnel [+2]

History of neurological conditions [+11]

Status: Not yet recruiting

Work-Related Health Factors in General and Special Education Teachers

This cross-sectional study aims to compare work-related health outcomes between general education teachers and special education teachers. The study will assess burnout, occupational balance, perceived stress, musculoskeletal symptoms, pain characteristics, and general job satisfaction. Participants will complete an online questionnaire including sociodemographic and occupational characteristics, such as age, sex, teaching experience, working hours, and type of teaching assignment. Standardized self-report measures will be used to evaluate burnout, occupational balance, perceived stress, musculoskeletal symptoms, and pain-related characteristics. The study will examine whether teachers working in special education differ from general education teachers in terms of burnout, stress, occupational balance, musculoskeletal problems, and pain. The findings may help identify occupational health needs among teachers and support the development of preventive strategies for improving their well-being and working conditions.

Participants needed: 200
Trial details
Biological sex: AllType: ObservationalSponsor: Lokman Hekim UniversityUpdated: Jul 1, 2026Locations: 1
Eligibility criteria

Aged 18 years or older. [+4]

Not currently working as a teacher during the data collection period (e.g., on l... [+2]

Status: Not yet recruiting

Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses

Newly graduated nurses often experience high levels of psychological stress, sleep disturbance, fatigue, and burnout during the early transition into clinical practice. Early identification of burnout and retention risk may help improve mental well-being, workforce stability, and quality of patient care. This longitudinal observational study aims to develop a non-invasive sleep-based prediction platform for assessing burnout and retention risk among postgraduate nurses. Participants will undergo repeated psychological assessments and non-contact sleep monitoring during the study period. Sleep-related physiological parameters, including sleep efficiency, sleep structure, heart rate variability, and respiratory variability, will be collected together with validated psychological questionnaires. The study will further apply machine learning and artificial intelligence approaches to integrate longitudinal physiological and psychological data for risk prediction and early identification of burnout-related conditions. The findings may support future development of precision mental health monitoring and supportive management strategies for high-stress healthcare workers.

Participants needed: 100
Trial details
Age: 20-65Biological sex: AllType: ObservationalSponsor: Kaohsiung Armed Forces General HospitalUpdated: Jun 24, 2026Locations: 1
Eligibility criteria

Newly employed postgraduate nurses within the first 3 months of clinical practic... [+5]

Diagnosed severe sleep disorders [+4]

Status: Not yet recruiting

Virtual Reality for Enhancing Self Compassion and Reducing Burnout Among Healthcare Providers

Healthcare providers in high-demand clinical settings are at high risk for burnout and secondary traumatic stress due to repeated exposure to patient trauma, which can compromise well-being and quality of care. Compassion-focused cognitive behavioral therapy (CF-CBT) can reduce stress and enhance self-compassion, but traditional delivery is time- and resource-intensive. This project evaluates the feasibility, acceptability, and potential effectiveness of virtual reality (VR)-enhanced CF-CBT specifically adapted for healthcare providers experiencing vicarious trauma. Grounded in Neff's self-compassion framework (emphasizing self-kindness, common humanity, and mindfulness) the VR intervention provides 8 immersive environments where participants can practice compassion-focused skills, engage in procedural learning, and regulate emotional responses in real time. The study will be conducted at UC San Diego Health using a two-arm randomized design comparing VR-enhanced CF-CBT with self-guided compassion-focused CBT/mindfulness exercises delivered without VR. Participants will complete 8 brief VR interventional sessions (approximately 6-10 minutes each) over 4-6 weeks. Outcomes include self-compassion, burnout, and secondary traumatic stress, measured using validated instruments. Feasibility and acceptability will be evaluated through recruitment, retention, session completion, engagement, and participant feedback. Findings will provide preliminary evidence for VR-enhanced compassion-focused interventions as a scalable and accessible approach to supporting healthcare providers' emotional well-being in demanding clinical environments, and will inform future cultural adaptation and implementation in low-resource and conflict-affected healthcare settings such as those in post-war zones.

Participants needed: 52
Trial details
Biological sex: AllType: InterventionalSponsor: University of California, San DiegoUpdated: Jun 24, 2026
Eligibility criteria

have at least one year of experience working in a healthcare setting

participating in other behavioral interventions that could confound study result... [+2]

Status: Not yet recruiting

A Study of a Mental Fitness Intervention for Anesthesiology Resident Wellbeing and Self-Compassion

The goal of this clinical trial is to learn if app-based wellness programs can help improve wellbeing and self-compassion for medical residents. This is a pilot study, which is done on a small group of people to learn if a larger study would be useful. The main questions it aims to answer are: 1. Are app-based wellness interventions feasible and acceptable in a high-stress population like medical residents? 2. Can app-based wellness programs improve wellbeing and self-compassion in medical residents? Researchers will compare the app-based wellness program to a time- and attention-matched control program. Participants will: * Complete online questionnaires at the start of the study and again after completion of the wellness program * Be assigned by chance (like a coin toss) to one of two different app-based programs, and will participate in the assigned program for 6 weeks. Both programs will involve weekly lessons and brief, daily exercises. Engagement with these exercises will not be mandatory but highly encouraged.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Jun 16, 2026Locations: 2
Eligibility criteria

Current PGY4 anesthesiology resident at Massachusetts General Hospital or Brigha... [+5]

Inability to complete English-language questionnaires [+3]

Status: Not yet recruiting

XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers

This study investigates the effectiveness of an extended reality (XR) based resilience training program designed to support the mental health and well-being of nurses working in hospital settings. Nurses are exposed to high emotional, cognitive, and organizational demands and show elevated levels of work-related stress and stress-associated mental health problems. Strengthening resilience and coping capacities is therefore an important preventive approach to support nurses' well-being and sustain quality of care. The study is conducted as a pragmatic randomized controlled trial with a waitlist control group and includes approximately 232 nurses from hospitals in several European countries. Participants are randomly assigned either to an XR-based resilience training group or to a waitlist control group that continues with care as usual during the waiting period. The XR-based intervention consists of eight immersive training sessions delivered over approximately ten weeks using a head-mounted display. The training focuses on behavioral, cognitive, and emotional coping strategies and aims to enhance key resilience factors such as problem-solving, cognitive reappraisal, emotion regulation, and positive self-care. The primary outcome is perceived stress, assessed using the Perceived Stress Scale. Secondary outcomes include resilience, occupational self-efficacy, quality of life, psychological distress, burnout symptoms, coping strategies, work-related rumination, and turnover intentions. Assessments are conducted at baseline, post-intervention, and at a 20-week follow-up. In addition, a subgroup of participants will optionally provide physiological data during selected XR sessions to explore digital biomarkers related to stress and recovery. The findings of this study will provide evidence on the effectiveness, feasibility, and acceptance of XR-based resilience training for nurses and inform future implementation of digital mental health interventions in healthcare workplaces.

Participants needed: 232
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Medical University of GrazUpdated: May 18, 2026Locations: 8
Eligibility criteria

working as a nurse in direct patient care within a clinical setting; [+4]

a diagnosed severe mental disorder associated with alterations in reality percep... [+5]

Status: Recruiting

The Effect of Student-Midwife Support Circle Intervention on Burnout, Resilience, and Professional Belonging Levels of Midwifery Students

Midwifery students are exposed to multifaceted stressors such as traumatic and unsupportive clinical experiences and psychosocial burdens; this can negatively impact emotional well-being, leading to secondary traumatic stress, burnout, compassion fatigue, and decreased sense of belonging. In this context, there is a growing need for structured and supportive interventions aimed at strengthening students' self-efficacy, resilience, and perceptions of social support. The aim of this research is to determine the effect of the Student Midwife Support Circle Intervention on midwifery students' levels of burnout, resilience, and professional belonging.

Participants needed: 80
Trial details
Age: 18-49Biological sex: FemaleType: InterventionalSponsor: Amasya UniversityUpdated: May 14, 2026Locations: 1
Eligibility criteria

Individuals who agree to participate voluntarily in the study [+1]

Individuals who do not agree to participate voluntarily in the study, [+1]

Status: Recruiting

A Tool of the Future for Strengthening Compassion in a Danish Hospital Setting.

This study is a multi-phase, mixed-methods clinical investigation designed to examine the feasibility, validity, and organizational applicability of a structured measurement framework for assessing compassion in a Danish hospital setting. The study is conducted at Herlev and Gentofte Hospital and involves both patients and healthcare professionals across multiple clinical departments. The study is structured in three sequential phases, each addressing distinct methodological and implementation components. Phase 1 (Translation and Cultural Adaptation): The initial phase involves the linguistic translation and cultural adaptation of three versions of the Sinclair Compassion Questionnaire (SCQ) and associated healthcare professional measures. This process follows established international guidelines for cross-cultural validation, including forward translation, back-translation, expert panel review, and pilot testing. Cognitive interviewing techniques are used to evaluate comprehension, relevance, and cultural appropriateness among both patients and healthcare professionals. Particular attention is given to semantic equivalence and the contextual meaning of key constructs across languages and professional groups. Phase 1b (Psychometric Validation): Following adaptation, the instruments are administered to a patient sample recruited from departments of anesthesia, surgery, and intensive care. Data collected in this phase are used to assess the psychometric properties of the translated instruments, including internal consistency, construct validity, factor structure, and measurement invariance. Statistical analyses include confirmatory factor analysis and reliability testing. The aim of this phase is to ensure that the instruments demonstrate robust measurement properties within the Danish healthcare context. Phase 2 (Observational Implementation Study): In the second phase, the validated instruments are implemented across four hospital departments, including medical, nephrology, orthopedic surgery, and emergency care. Data are collected from both patients and healthcare professionals to allow for multi-perspective analysis. In addition to questionnaire data, contextual variables such as demographic characteristics, professional background, and organizational factors are recorded. Administrative data, including sick leave and workforce indicators, are incorporated where available. This phase employs a cross-sectional observational design with embedded comparative analyses across departments and professional groups. Multilevel modeling approaches are used to account for clustering within departments and to explore variation at individual and organizational levels. The design enables identification of patterns and differences across settings without introducing experimental manipulation. Phase 3 (Contextualized Implementation and Development): The third phase involves the application of findings from earlier phases to inform targeted implementation strategies. Rather than introducing a predefined intervention, this phase adopts an adaptive approach in which context-specific initiatives are selected or developed based on identified needs. This may include integration of existing training programs, workflow adjustments, or development of new tools. The implementation process is supported by interdisciplinary collaboration, including expertise in clinical practice, education, and organizational development. Data Collection and Management: Data are collected using secure electronic platforms compliant with Danish data protection regulations. All participant data are handled in accordance with GDPR requirements. Identifiable data are stored separately from research data, and access is restricted to authorized personnel. Data quality assurance procedures include validation checks and standardized data entry protocols. Participant Involvement: Patients are recruited during their contact with hospital departments and provide self-reported data through questionnaires. Healthcare professionals participate by completing self-assessment measures. Participation is voluntary, and no experimental interventions are administered. Statistical Considerations: The study uses both descriptive and inferential statistical methods. Psychometric analyses are conducted in Phase 1b, while Phase 2 includes regression analyses and multilevel modeling to examine associations between variables. Missing data are handled using appropriate statistical techniques, such as multiple imputation where relevant. Ethical Considerations: The study adheres to ethical guidelines for clinical research involving human participants. Informed consent is obtained from all participants. Participation does not influence clinical care or employment conditions. The study design minimizes participant burden by integrating data collection into existing clinical workflows where possible.

Participants needed: 2,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Herlev and Gentofte HospitalUpdated: May 14, 2026Locations: 1
Eligibility criteria

A patient at either the a. Department of Nephrology, b. Department of Internal M... [+4]

Age 0-17 [+10]

Status: Not yet recruiting

Effect of an Empowerment-Based Psychoeducation Program on Burnout and Psychological Outcomes in Nurse Managers

This randomized controlled trial aims to evaluate the effectiveness of an empowerment-based psychoeducation program on burnout, self-leadership, mindfulness, and psychological resilience among nurse managers. The study population consists of nurse managers working in healthcare settings. The primary objective of this study is to determine whether the psychoeducation program reduces burnout levels and improves self-leadership, mindfulness, and psychological resilience among nurse managers. The main research questions are as follows: Does the empowerment-based psychoeducation program reduce burnout levels in nurse managers? Does the program improve self-leadership levels in nurse managers? Does the program increase mindfulness levels in nurse managers? Does the program enhance psychological resilience in nurse managers? In this randomized controlled design, participants will be assigned to either an intervention group or a control group. The intervention group will receive a structured empowerment-based psychoeducation program lasting five weeks, while the control group will not receive any intervention. Participants will undergo the following procedures: Completion of baseline (pre-test) assessments (T1) Participation in the psychoeducation program for the intervention group (5 weeks) No intervention for the control group Completion of post-intervention assessments (T2) Completion of follow-up assessments three months after the intervention (T3) The findings of this study are expected to contribute to the development of evidence-based interventions aimed at strengthening managerial competencies and psychological well-being among nurse managers.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Suleyman Demirel UniversityUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Nurse managers currently working in healthcare institutions [+4]

Participation in a similar psychoeducation or intervention program within the la... [+2]

Status: Recruiting

The WISER Study: Web Based Methods for Enhancing Resilience

This is a research study to find out if web-based resilience tools can increase well-being. Enrolled participants will try out one or more brief positive psychology tools. The tools ask participants to reflect on positive experiences or to do an activity (e.g., write a letter of gratitude). The study is entirely online and participants will be prompted to participate via email or text messages. The study team is interested in the effects of the tools on stress, depression, and burnout in adults. A set of brief surveys are administered before and after using the tool, and again at follow-up periods (e.g., 1, 3, 6 and 12 months). Surveys are collected electronically using the secure, HIPAA-compliant survey software. There is no direct benefit to participants for participating in this research study aside from the potential to experience improvements in well-being. Risks are minimal and include the potential to feel emotional or psychological distress when asked questions related to burnout.

Participants needed: 8,000
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: Apr 8, 2026Locations: 1
Eligibility criteria

Adults 18 and over are considered eligible for the study. A sub-sample will incl...

Adults who are not proficient in English, do not have basic computer skills, or...

Status: Not yet recruiting

Empowerment Training for Personal Agency Development of Primary Health Care Workers

This study evaluates an Empowerment Agency Training (EAT) intervention within the SPHERES programme that aims to strengthen personal agency among workers in primary healthcare centers (Puskesmas) in Indonesia. The intervention focuses on building self-efficacy, behavioural control, leadership, and intentional decision-making through structured training, follow-up action planning, observational support, and sustainability-oriented incentives. Strengthening personal agency is expected to improve the use of data for decision-making and the delivery of priority primary health services at the Puskesmas level.

Participants needed: 200
Trial details
Biological sex: AllType: InterventionalSponsor: Oxford University Clinical Research Unit IndonesiaUpdated: Apr 3, 2026Locations: 2
Eligibility criteria

PHC staff who decline to provide informed consent. [+2]

Status: Not yet recruiting

Professional Readiness Through Emotional Preparedness (PREP)

The purpose of this study is to examine the impact of the PREP program on participants' psychological and occupational well-being, and work readiness

Participants needed: 212
Trial details
Biological sex: AllType: InterventionalSponsor: AdventHealthUpdated: Mar 16, 2026Locations: 1
Eligibility criteria

Nurse resident employed by AdventHealth working in acute care/hospital setting [+3]

Not in a current RN residency program [+1]

Status: Not yet recruiting

On-Demand AI Support Via LINE-Based GPT Assistant to Improve Emotional Resilience and Reduce Burnout Among Clinical Nurses

Clinical nurses are frequently exposed to high emotional demands due to heavy workloads, time pressure, patient suffering, and the interpersonal complexity of clinical care. These stressors may contribute to compassion fatigue, burnout, reduced resilience, and decreased occupational well-being. However, timely and accessible psychological support is often limited in busy clinical environments, and many nurses may hesitate to seek help due to stigma, time constraints, or limited resources. This study is a prospective, randomized, controlled, parallel-group interventional trial designed to evaluate the feasibility and effectiveness of an on-demand, human-centered emotional support intervention delivered through a LINE-based GPT assistant. The AI assistant provides real-time supportive conversations, reflective prompts, stress-coping guidance, and resilience-enhancing strategies tailored specifically for clinical nurses, offering a private and easily accessible support resource. Eligible clinical nurses (target sample size: 100-120) are randomly assigned to either an Intervention Group, which interacts with the AI assistant, or a Control Group, which receives non-interactive static messages, over a four-week intervention period. Primary outcomes include changes in compassion fatigue, burnout, and compassion satisfaction, as measured by the Professional Quality of Life Scale (ProQOL). Secondary outcomes include changes in resilience (Brief Resilience Scale), general self-efficacy (General Self-Efficacy Scale), and perceived stress (Perceived Stress Scale-10). The results of this study are expected to provide evidence on the feasibility and potential effectiveness of AI-based emotional support as a scalable and accessible tool to promote psychological well-being among clinical nurses, thereby informing future digital mental health interventions in healthcare settings.

Participants needed: 120
Trial details
Age: 20-65Biological sex: AllType: InterventionalSponsor: Taipei Medical University Shuang Ho HospitalUpdated: Mar 11, 2026
Eligibility criteria

Adults aged 20 to 65 years. [+4]

Refusal or inability to provide informed consent. [+3]

Status: Recruiting

A Pilot Study of RISE for Nurse Managers Retreat

The purpose of this study is to determine the feasibility and acceptability of the RISE for Nurse Managers retreat and its impact on occupational and psychological well-being indicators

Participants needed: 16
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: AdventHealthUpdated: Feb 19, 2026Locations: 1
Eligibility criteria

an employed AdventHealth Nurse Manager [+1]

a direct care RN, Nurse Director, Educator, and Executive [+1]

Status: Recruiting

Heart Rate Variability Biofeedback in Security Forces

This exploratory study evaluates the effectiveness of a 12-session Heart Rate Variability Biofeedback (HRV-BFB) protocol in reducing distress and burnout while promoting psychological well-being among Portuguese National Republican Guard (GNR) professionals. Exposed to high occupational stress from unpredictable risks, shift work, and limited resources, these individuals face elevated vulnerability to chronic stress outcomes. The intervention leverages real-time HRV feedback to enhance autonomic regulation, breathing techniques, and emotional self-regulation.

Participants needed: 50
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Egas Moniz - Cooperativa de Ensino Superior, CRLUpdated: Feb 6, 2026Locations: 1
Eligibility criteria

Operational military personnel of the Guarda Nacional Republicana (GNR) performi... [+4]

Extended sick leave or medical absence [+2]

Status: Not yet recruiting

Online Parenting Support With VIPP-SD in Chile

The goal of this randomized controlled trial is to test whether the online Video-feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) can reduce parental burnout and improve parenting practices, in mothers of young children in Chile. The main questions it aims to answer are: * Does the online VIPP-SD increase maternal sensitivity and the use of consistent but gentle limit setting? * Does it reduce parental burnout? * Does it improve parental stress and child attachment security and reduce child conduct problems? Researchers will compare families who receive the online VIPP-SD to families in a waitlist control group with dummy treatment to see if VIPP-SD has benefits for parents and children. Participants will be mothers of children aged 11-16 months at the start of the study who report elevated levels of parental burnout. Mothers in the intervention group will: * Take part in 12 weekly online sessions with a trained intervener * Receive video-feedback on their own interactions with their child * Learn strategies to respond sensitively to their child's needs and to use positive discipline The study will also measure potential moderators such as maternal mental health, child temperament, and family sociodemographic factors.

Participants needed: 140
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Universidad San SebastiánUpdated: Jan 26, 2026
Eligibility criteria

Mothers >18 years [+4]

Child or parent with severe sensory impairment, learning disability, or language... [+3]

Status: Not yet recruiting

Prevalence of Psychiatric Problems Among Patients and Healthcare Providers in a Cardiology Department: A Cross-Sectional Study

The goal of this observational cross-sectional study is to determine the prevalence of psychiatric problems (depression, anxiety, stress, and burnout) among patients with cardiovascular diseases and healthcare providers working in the Department of Cardiovascular Medicine at Assiut University Heart Hospital. The main questions it aims to answer are: * What is the prevalence of depression, anxiety, and stress among cardiovascular patients? * What is the prevalence of burnout, depression, and anxiety among healthcare providers in the same department? The study will also explore potential sociodemographic, occupational, and clinical factors associated with these psychological outcomes.

Participants needed: 380
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Dec 10, 2025Locations: 1Duration: 1 Day
Eligibility criteria

Not listed