Athletic Performance

35

Review clinical trials related to Athletic Performance. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Neuroscience-Based Exercise Training in Female Volleyball Players

24 volunteer professional female volleyball players (aged 16-21), licensed in the Turkish Volleyball Federation (TVF) Women's Volleyball League 2 and 3, will be included in the study. Participants will be randomized into intervention (n=12) and control (n=12) groups using www.randomizer.org. The intervention group will receive an 8-week (3 days/week) neuro-athletic exercise training program, including eye warm-up exercises and volleyball-specific visual and motor coordination stations, in addition to their regular training. The control group will continue with regular training only. Both groups will have equal total training time. Visual attention and decision-making strategies will be measured with a wearable eye-tracking system (Pupil Labs Invisible) during a serve task. Cortical activation (oxygenated and deoxygenated hemoglobin levels) in the frontal cortex during the same serve task will be measured simultaneously with functional near-infrared spectroscopy (fNIRS). Sport-specific physical fitness will be evaluated with the T-Agility Test, radar gun serve speed measurement, VERT wearable jump analysis system, Y-Balance Test, and sit-and-reach test. All assessments will be conducted before training begins and after the 8-week program. The study aims to determine whether neuro-athletic exercise training improves cortical activation, visual attention, decision-making processes, and sport-specific physical fitness parameters in professional female volleyball players, compared to a control group receiving regular training only.

Participants needed: 24
Trial details
Age: 16-21Biological sex: FemaleType: InterventionalSponsor: Özge Ecem ŞenelUpdated: Oct 2, 2026Locations: 1
Eligibility criteria

Licensed female volleyball player in the Turkish Volleyball Federation (TVF) Wom... [+2]

Any history of musculoskeletal surgery [+2]

Status: Not yet recruiting

A Multiphase Analysis of Next-generation Trail Footwear

This study will investigate how different advanced-foam trail-running footwear configurations affect running economy, performance, comfort, and fatigue in competitive trail runners. The project aims to determine whether footwear characteristics, particularly foam properties and stack height, influence physiological and biomechanical responses during both controlled laboratory running and real-world trail running. Approximately 30 competitive trail runners with experience in technical trail running and no musculoskeletal injury during the previous six months will participate. The study will use a two-phase experimental design. In Phase 1, participants will complete running economy assessments in three footwear conditions in randomized order. The footwear conditions will include a high-stack advanced-foam prototype, a medium-stack advanced-foam prototype, and a conventional-foam shoe. Laboratory testing will be performed during uphill and downhill treadmill running. Participants will also complete field-based running economy trials on real trail terrain at a controlled speed, followed by a short time trial to establish a representative running pace. In Phase 2, participants will complete prolonged trail-running sessions in the two advanced-foam footwear configurations on a 15-km trail course. Running economy and fatigue-related responses will be assessed repeatedly during the prolonged exercise sessions to evaluate changes in physiological and biomechanical efficiency over time. The primary physiological outcome will be running economy, assessed through oxygen consumption and energy cost. Additional outcomes will include heart rate, step frequency, step length, ground contact time, perceived exertion, comfort, perceived performance, and pacing-related measures. The study will compare laboratory and field responses to determine whether differences in running economy observed under controlled conditions are maintained during real trail running and whether footwear configuration influences the deterioration of running economy and fatigue during prolonged exercise.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Fernando González-Mohíno MayoralasUpdated: Oct 2, 2026
Eligibility criteria

Competitive trail runners. [+2]

Musculoskeletal injury in the previous 6 months.

Status: Not yet recruiting

Effect of KA-EX Supplementation on Recovery Parameters in High-Level Young Football Players

The purpose of this study is to evaluate the effects of KA-EX supplementation on recovery parameters in elite young football players. Athletes from the Udine Primavera team will be randomly assigned to receive either the KA-EX supplement or a sensory-matched placebo immediately following their training sessions for a period of two months. The researchers will monitor heart rate variability (HRV) and sleep quality using Garmin wearable devices, and assess changes in body composition using Dual-energy X-ray absorptiometry (DEXA) and bioelectrical impedance analysis (BIA). The goal of the study is to determine if post-training KA-EX administration improves physiological recovery, sleep quality, and physical readiness in high-performance athletes during a competitive season.

Participants needed: 25
Trial details
Age: 17-20Biological sex: MaleType: InterventionalSponsor: Antonio Molina LopezUpdated: Sep 17, 2026Locations: 1
Eligibility criteria

Membership of the Udine Primavera team at the time of the study. Regular partici...

Presence of any injury or medical condition that limits normal participation in...

Status: Recruiting

TCP-600 Supplementation and Performance Response in Professional Football Players

This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function, recovery-related readiness, and selected football-specific perceptual-cognitive performance. Participants will be randomly assigned to receive either placebo or a phosphatidylserine-containing multi-ingredient supplement. Before and after the supplementation period, players will complete non-invasive assessments such as sprint testing, reaction-time testing, heart rate variability monitoring, wellness/readiness questionnaires, mental-fatigue measures, and selected football-specific perceptual-cognitive tasks where available. The study is designed as an external validation and extension of responder profiles derived from previous randomized controlled trials. Data from previous trials and this validation cohort will be used to examine whether baseline physical, cognitive, autonomic, fatigue-related, recovery-related, or perceptual-cognitive characteristics can predict which players are most likely to benefit from phosphatidylserine-containing multi-ingredient supplementation.

Participants needed: 65
Trial details
Age: 18-37Biological sex: MaleType: InterventionalSponsor: Vizja University in WarsawUpdated: Sep 8, 2026Locations: 3
Eligibility criteria

Male professional or highly trained football players aged 18-37 years. [+9]

Current musculoskeletal injury or illness preventing full participation in train... [+10]

Status: Not yet recruiting

Core Strength Training, Anthropometry, and Postural Control in Youth Optimist Sailors

Optimist dinghy sailing is a highly demanding youth watersport characterized by prolonged, high-intensity isometric hiking postures and rapid dynamic weight shifts required to preserve boat trim, balance, and sail power output. The core (lumbar-pelvic-hip complex) functions as the central dynamic link in transferring kinetic forces between the lower limbs and trunk during continuous open-water maneuvers. This study is designed as a 12-week randomized controlled interventional trial to evaluate the effects of a periodized, circuit-based Core Strength Training (CST) program integrated into routine Technical Sailing Training (TST) compared to TST alone. Primary endpoints evaluate adaptations in the anthropometric profile (skinfold thickness, circumferences, muscle mass percentage) and postural control parameters (Center of Pressure displacement and sway velocity measured via computerized force platform posturography) in competitive youth Optimist sailors.

Participants needed: 40
Trial details
Age: 8-15Biological sex: AllType: InterventionalSponsor: University of FoggiaUpdated: Sep 3, 2026Locations: 1
Eligibility criteria

Active competitive youth Optimist class dinghy sailors aged between 8 and 15 yea... [+4]

Acute or chronic musculoskeletal injuries affecting the spine, abdominal wall, l... [+3]

Status: Not yet recruiting

Effects of Different Sled Loads on Sprint and Neuromuscular Performance in Young Male Football Players: An 8-Week Periodized Field Study

The purpose of this 8-week periodized field study is to investigate and compare the acute and chronic effects of three different sled towing loads (10%, 15%, and 20% of body weight \[BW\]) on sprint performance (5m, 10m, 15m) and neuromuscular characteristics (Squat Jump \[SJ\], Countermovement Jump \[CMJ\], Drop Jump \[DJ\], and Reactive Strength Index \[RSI\]) in trained male youth football players aged 13-14 years. While all other training variables (distance, frequency, volume, and rest intervals) are standardized, this study aims to identify the optimal sled load that enhances acceleration and horizontal force production without compromising running mechanics during a critical pediatric athletic development window.

Participants needed: 30
Trial details
Age: 13-14Biological sex: MaleType: InterventionalSponsor: Bitlis Eren UniversityUpdated: Sep 1, 2026Locations: 1
Eligibility criteria

Male football players aged chronologically between 13 and 14 years. [+4]

Chronological age <13 or >14 years. [+5]

Status: Not yet recruiting

Respiratory Muscle Strength and Jiu-Jitsu-Specific Performance in Male Brazilian Jiu-Jitsu Athletes

Brazilian Jiu-Jitsu (BJJ) is an intermittent combat sport that requires repeated high-intensity efforts and sustained gripping. This analytical cross-sectional study will examine whether respiratory muscle strength is associated with BJJ-specific anaerobic performance and static kimono grip endurance in adult male BJJ athletes. Forty athletes will attend three assessment visits separated by 48 to 72 hours. Maximal inspiratory pressure, maximal expiratory pressure, and spirometric indices (forced vital capacity \[FVC\], forced expiratory volume in 1 second \[FEV1\], FEV1/FVC ratio, and peak expiratory flow \[PEF\]) will be measured at the first visit. The Jiu-Jitsu Anaerobic Performance Test and the Maximum Static Kimono Grip Test will be completed at the other two visits in randomized order. The primary analysis will examine the association between maximal inspiratory pressure and the total number of valid repetitions completed during the Jiu-Jitsu Anaerobic Performance Test. Spirometric indices will be evaluated as secondary outcomes.

Participants needed: 40
Trial details
Age: 18-40Biological sex: MaleType: ObservationalSponsor: Halic UniversityUpdated: Aug 31, 2026Locations: 1
Eligibility criteria

Male sex [+6]

Diagnosed cardiovascular, respiratory, neurological, metabolic, or musculoskelet... [+4]

Status: Recruiting

Endurance Trial: Ketone and Carbohydrate Supplementation

This randomized, double-blind, crossover study investigates the effects of exogenous ketone supplementation on physical and cognitive performance in amateur endurance athletes during exhaustive exercise. Participants will complete three 3-hour cycling sessions under different nutritional conditions: carbohydrate alone (CHO), carbohydrate plus ketone (CHO-KET), and placebo (PLA). The study will assess cognitive function through validated computerized tests, physical performance via distance covered, and metabolic responses through blood biomarkers. Additionally, peripheral blood mononuclear cells (PBMCs) will be collected and cultured with LPS or not. Other PBMCs co-cultured with neuronal cells (SH-SY5Y) to investigate neuro-immune interactions. The primary hypothesis is that ketone supplementation will preserve cognitive function and enhance physical performance during prolonged exhaustive exercise compared to carbohydrate supplementation alone, potentially through anti-inflammatory mechanisms and alternative energy substrate provision.

Participants needed: 12
Trial details
Age: 20-50Biological sex: MaleType: InterventionalSponsor: University of Sao PauloUpdated: Aug 28, 2026Locations: 1
Eligibility criteria

Amateur male cyclists; [+3]

Confirmed diagnosis of COVID-19 by PCR or rapid antigen test within the last 12... [+10]

Status: Not yet recruiting

Mental Fatigue, Attentional Focus, and Countermovement Jump Performance

This study examines whether short-term mental fatigue and different jump instructions affect how high people can jump. Thirty-two physically active university students will complete two testing sessions in random order: one after a 30-minute mentally tiring computer task and one after a 30-minute relaxing video. In both sessions, participants will perform vertical jumps while receiving one of three types of instructions: no special instruction, focusing on their own body movements, or focusing on pushing the ground away. The study will compare jump height across these conditions to better understand how mental tiredness and coaching cues affect jumping performance, which may help coaches and athletes design better training and competition preparation.

Participants needed: 32
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Inonu UniversityUpdated: Aug 21, 2026Locations: 1
Eligibility criteria

Age 18-30 years [+4]

Major lower-extremity surgery or injury [+4]

Status: Recruiting

The Impact of the Menstrual Cycle on Physical Exercise and Performance

The menstrual cycle implies a basic difference in the biology of women and men but the effect of the hormonal variation on training protocols and physical performance is still not fully understood. Despite no existing evidence, the advice to periodize exercise according to the menstrual cycle has been widely spread among elite athletes, coaches, and sports federations. The advice is based on underpowered studies with considerable methodological weaknesses regarding determination of cycle phase, inclusion of athletes and lack of adequate control groups. The purpose of this randomized, controlled study is to evaluate the effect of exercise periodization on aerobic fitness during different phases of the menstrual cycle. Further, the effect will be related to premenstrual symptoms, body composition and skeletal muscle morphology, sex hormone receptors, metabolic enzymes, and markers of muscle protein synthesis. This study will be well controlled and follow methodology recommendations for menstrual cycle research in sports and exercise. Female athletes of fertile age will be randomized to different training regimens during three menstrual cycles (12 weeks): Group A: Training three times a week throughout the menstrual cycle. Group B: Follicular phase-based training five times a week during the follicular phase and thereafter once a week during the luteal phase. Group C: Luteal phase-based training five times a week during the luteal phase and once a week in the follicular phase. The exercise will consist of high intensity intermittent spinning classes. Assessment of aerobic fitness and power will be performed at baseline, and again after three completed menstrual cycles. On the same day, body composition will be examined by DXA and blood samples will be collected for analysis of hormones and binding proteins. To confirm menstrual cycle phase, blood samples will be collected for hormone determination, and urinary stick will be used for detection of ovulation. Subjective ratings of menstrual cycle related symptoms will be performed every day. In a subgroup of women, muscle biopsies will be collected from m vastus lateralis at baseline and at the end of the study. This study will contribute to improved knowledge about exercise periodization in relation to the menstrual cycle. Well-grounded data is crucial to give evidence-based recommendations to female athletes when planning their training protocol to optimize training results and performance.

Participants needed: 111
Trial details
Age: 18-35Biological sex: FemaleType: InterventionalSponsor: Karolinska InstitutetUpdated: Aug 13, 2026Locations: 1
Eligibility criteria

Women exercising at least 3-4 times a week on a high level [+2]

Hormonal contraceptive users, [+4]

Status: Recruiting

Acute Effects of Functional Inspiratory Muscle Training in Elite Male Volleyball Players

This randomized controlled trial evaluates the acute effects of a single session of functional inspiratory muscle training on muscle oxygenation, exercise capacity, dynamic balance, and agility in elite male volleyball players aged 18 to 25 years. Thirty participants will be randomly assigned in a 1:1 ratio to an intervention group or a no-intervention control group. The intervention group will perform 60 resisted breaths at 50% of maximal inspiratory pressure using a POWERbreathe device during a sport-specific fixed-ball throwing drill. Both groups will complete assessments before and immediately after the intervention period on the same day. Quadriceps muscle oxygen saturation and total hemoglobin will be measured using a Moxy near-infrared spectroscopy monitor during the Incremental Shuttle Walk Test. Exercise capacity, dynamic balance, and agility will be assessed using the Incremental Shuttle Walk Test, Star Excursion Balance Test, and T-Test, respectively.

Participants needed: 30
Trial details
Age: 18-25Biological sex: MaleType: InterventionalSponsor: Gazi UniversityUpdated: Aug 13, 2026Locations: 1
Eligibility criteria

Male, aged 18 to 25 years [+4]

Current smoking or regular alcohol use [+5]

Status: Not yet recruiting

The Effects of Acute Nitrate and Caffeine Co-ingestion on Discipline-Specific Exercise Performance.

The purpose of this study is to investigate the acute, separate, and combined ergogenic effects of dietary nitrate (beetroot juice, BJ) and caffeine (CAF) supplementation on discipline-specific athletic performance. The project employs a double-blind, randomized, placebo-controlled, four-arm crossover design. It evaluates two highly distinct, heterogeneous populations of athletes: (A) adult high-intensity functional training (HIFT/CrossFit/Hyrox) competitors performing the standardized Hyrox Physical Fitness Test (P'F'T), and (B) elite junior competitive swimmers (National Team members) performing a progressive 8 × 100 m swimming test. The study will assess physical performance, lactate kinetics, subjective exertion, biochemical indices, psychological metrics, and gastrointestinal tolerance.

Participants needed: 112
Trial details
Age: 16-45Biological sex: AllType: InterventionalSponsor: Poznan University of Physical EducationUpdated: Aug 7, 2026Locations: 1
Eligibility criteria

Aged 18-45 years. [+15]

Occurrence of acute musculoskeletal injury or trauma during the study period. [+2]

Status: Not yet recruiting

The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players

The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players. The main questions it aims to answer are: 1. Does sodium citrate improve sprint times, peak power, minimum power, and mean power during repeated sprints? 2. Does sodium citrate lower fatigue index (the drop in power across sprints) during repeated sprint exercise? 3. Does sodium citrate change blood bicarbonate, pH, and lactate levels before and after exercise? 4. Does sodium citrate affect how hard exercise feels (perceived exertion)?

Participants needed: 20
Trial details
Age: 18-25Biological sex: FemaleType: InterventionalSponsor: Hacettepe UniversityUpdated: Jul 30, 2026
Eligibility criteria

Female professional soccer players competing in the Turkish Women's Third League [+6]

Use of oral contraceptives [+6]

Status: Recruiting

HME Amino Acid Supplementation for Strength, Performance, and Recovery in Trained Adult Males

This pilot randomized controlled trial evaluates HME (Human Muscle Equivalent), a free-form amino acid supplement formulated to match the amino acid composition of human skeletal muscle, taken at its Health Canada licensed dose (3 g powder plus one 50 mg slow-release beta-alanine capsule daily). Trained adult males (competitive athletes or certified fitness professionals) are randomized to HME or an identical-appearing placebo for 10 weeks: a 2-week supplement-only lead-in followed by 8 weeks of supplement plus supervised resistance training. The primary aim is to estimate the effect of HME on composite maximal strength (1-repetition maximum leg press plus chest press) compared with placebo. Secondary measures include isometric knee-extension strength, countermovement jump height, and subjective recovery.

Participants needed: 50
Trial details
Age: 18-45Biological sex: MaleType: InterventionalSponsor: Orivian incUpdated: Jul 23, 2026Locations: 1
Eligibility criteria

Age 18 to 45 years inclusive [+8]

Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other... [+6]

Status: Not yet recruiting

Acute Effects of Different Warm-Up Protocols in Amateur Basketball Players

Brief Summary This randomized controlled trial will compare the immediate effects of three warm-up protocols on physical performance in male amateur basketball players. A total of 45 licensed basketball players aged 15 to 25 years will be randomly assigned to one of three groups: standard dynamic warm-up, dynamic warm-up followed by classical hold-relax proprioceptive neuromuscular facilitation (PNF) stretching, or dynamic warm-up followed by short-duration self-administered PNF stretching. The main outcome will be the change in countermovement jump height. Additional outcomes will include flexibility, knee range of motion, squat jump height, 20-meter sprint time, agility, dynamic balance, and perceived exertion. Measurements will be performed before the assigned warm-up protocol, immediately after the protocol, and 15 minutes after the protocol. The study aims to determine whether short-duration self-PNF stretching can improve flexibility while preserving performance more effectively than classical PNF stretching. Each participant will complete the assigned protocol and all assessments during a single study session.

Participants needed: 45
Trial details
Age: 15-25Biological sex: MaleType: InterventionalSponsor: Istanbul Medipol University HospitalUpdated: Jul 23, 2026Locations: 1
Eligibility criteria

Male [+11]

Acute lower-extremity muscle, tendon, ligament, or bone injury [+9]

Status: Recruiting

Effects of Diaphragmatic Breathing Retraining in Combat Sport Athletes With Dysfunctional Breathing Patterns

Combat sport athletes often need to maintain a guarded posture, stabilize the trunk, react quickly, and control balance during contact or unexpected movement. These demands may be related not only to strength and conditioning, but also to the coordination between breathing and postural control. The diaphragm is the main muscle for breathing and also contributes to trunk stability through its role in pressure regulation and deep core control. However, dysfunctional breathing patterns, such as upper-chest dominant breathing, reduced lower rib expansion, or poor coordination between the chest and abdomen, may interfere with this function. The purpose of this study is to examine dysfunctional breathing patterns in combat sport athletes and to investigate whether diaphragmatic breathing retraining can improve breathing patterns, diaphragm function, core stability, postural control, and sport-related performance. This study will first screen athletes from combat and non-combat sports to determine the prevalence of dysfunctional breathing. Combat sport athletes will then complete laboratory tests to examine the relationship between breathing pattern, posture, diaphragm function, core stability, and postural control. In the intervention part of the study, combat sport athletes with dysfunctional breathing will be randomly assigned to diaphragmatic breathing retraining plus usual training or usual training only. The study will compare the two groups to determine whether adding diaphragmatic breathing retraining provides additional benefits. The study will also examine whether the changes are maintained after training and whether baseline measures can help identify athletes who respond better to the program.

Participants needed: 60
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: National Cheng Kung UniversityUpdated: Jul 21, 2026Locations: 1
Eligibility criteria

Aged between 18 and 50 years. [+2]

Current or major musculoskeletal injury within the past year that may affect tes... [+6]

Status: Recruiting

Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters

The purpose of this randomized controlled trial is to compare the effects of Nordic Hamstring Exercise (NHE) and Blood Flow Restriction-assisted Nordic Hamstring Exercise (BFR-NHE) on hamstring muscle strength, muscle morphology, and functional performance in elite adolescent female pole vaulters. Thirty-six athletes aged 12-18 years will be randomly assigned to a Nordic Hamstring Exercise group, a Blood Flow Restriction-assisted Nordic Hamstring Exercise group, or a control group. Intervention groups will participate in supervised exercise training three times per week for eight weeks, while the control group will continue routine sports training. Outcomes will be assessed before and after the intervention period.

Participants needed: 36
Trial details
Age: 12-18Biological sex: FemaleType: InterventionalSponsor: Toros UniversityUpdated: Jul 15, 2026Locations: 1
Eligibility criteria

Female athletes aged between 12 and 18 years. [+5]

Any lower extremity musculoskeletal injury within the previous 6 months. [+7]

Status: Recruiting

Effect of Reactive Balance Training Versus Conventional Balance Training on Dynamic Stability and Change-of-Direction Performance in Competitive Tennis Players

This randomized controlled trial aims to compare the effectiveness of reactive balance training versus conventional balance training on dynamic stability and change of direction performance. Participants will be randomly allocated into two groups. Each group will receive its respective intervention over a 6-week period. Outcome measures, including dynamic stability assessed by the Y-Balance Test and change-of-direction performance measured using the 505 Agility Test, will be evaluated at baseline and after the intervention. The study is designed to determine which training approach is more effective in improving balance and functional performance.

Participants needed: 64
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: Ibadat International University, IslamabadUpdated: Jun 26, 2026Locations: 1
Eligibility criteria

Male and female competitive tennis players aged 18-25 years. [+2]

Recent injury (last 3 months) [+4]

Status: Not yet recruiting

Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players

The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18. A total of 54 healthy soccer players will be included and randomly assigned into three equal groups: the Control Group, the Core Training Group, and the Core Training + IMT Group. All interventions will be implemented for 8 weeks in addition to routine soccer training sessions. Assessments will be performed at baseline (Week 0), mid-intervention (Week 4), and post-intervention (Week 8). The primary outcome measures of the study are aerobic capacity assessed by the Yo-Yo Intermittent Recovery Test Level 1 and muscle oxygenation parameters monitored via near-infrared spectroscopy (NIRS) using a MOXY monitor. Secondary outcome measures include sprint performance, agility, dynamic balance, core muscle strength and endurance, inspiratory muscle strength, lower extremity explosive power, and soccer-specific technical performance tests. Overall, this study aims to reveal the combined effects of core training and inspiratory muscle training on muscle oxygenation, respiratory functions, aerobic capacity, and soccer performance, while explaining the underlying physiological mechanisms in youth athletes.

Participants needed: 54
Trial details
Age: 15-18Biological sex: MaleType: InterventionalSponsor: Istinye UniversityUpdated: Jun 18, 2026Locations: 1
Eligibility criteria

Being between 15 and 18 years of age. [+7]

Having a history of lower extremity, trunk-core, or athletic performance-limitin... [+15]

Status: Recruiting

Acute Effects of Post-Exercise Hyperoxia on Recovery in Cycling

This study examines whether exposition to hyperbaric oxygen after a road-race simulation can help competitive cyclists recover and perform better the following day. Hyperbaric oxygen, which involves breathing oxygen inside a pressurized chamber, is used as a recovery method in elite and professional sport. Its effectiveness, however, remains controversial: despite this widespread use, there is a lack of solid scientific evidence that a single HBO session after strenuous endurance exercise actually improves recovery, or that clarifies how the amount of oxygen exposure influences any benefit. The study includes healthy male road cyclists between 18 and 40 years of age who compete at the national level in Belgium. After completing a fatiguing cycling session, each participant is randomly assigned to one of four groups receiving different levels of oxygen exposure during recovery. Two groups breathe oxygen under increased pressure inside a chamber at either 2.5 or 1.4 atmospheres absolute. A third group breathes oxygen at normal pressure. The fourth group receives a sham condition that reproduces the treatment setting without active oxygen exposure. The study is double-blind, meaning that neither the participants nor the researchers assessing the outcomes know which condition each participant receives. The main goal is to determine whether a single session of post-exercise HBO improves next-day endurance performance, and whether higher oxygen exposure produces greater effects. The researchers also collect blood samples and physiological measurements to better understand how the body recovers.

Participants needed: 48
Trial details
Age: 18-40Biological sex: MaleType: InterventionalSponsor: Université Catholique de LouvainUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Road cyclists competing in Elite 2 (Elite without professional contract) or Unde... [+4]

Presence of significant cardiovascular, pulmonary, neurological, ENT, or metabol... [+4]

Status: Recruiting

Squat Jump Performance and Chiropractic Ankle Manipulation

The goal of this clinical trial is to learn if chiropractic ankle manipulation can improve squat jump performance. It will also learn about the relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance. The main questions it aims to answer are: * Does chiropractic ankle manipulation increase squat jump height? * Is there a relationship among chiropractic ankle manipulation, ankle range of motion, and squat jump performance? Researchers will compare squat jump performance between subjects who receive chiropractic ankle manipulations with control subjects to see if ankle chiropractic manipulation works to improve squat jump performance. Participants will: * Visit the research laboratory for one testing session to measure ankle range of motion and squat jump performance, before and after their randomly assigned intervention arm * Receive either a chiropractic ankle manipulations or rest quietly as the control condition during the testing session.

Participants needed: 60
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Northeast College of Health SciencesUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

age range from 18 to 35 years old; and [+1]

professional or amateur ranked athlete; [+6]

Status: Not yet recruiting

UCLA Magnesium Formulation Athlete Study

This randomized, double-blind, placebo-controlled trial will compare magnesium glycinate, magnesium L-threonate, and placebo in UCLA varsity athletes. Participants will complete a baseline monitoring period followed by 4 weeks of blinded nightly supplementation. WHOOP or study-approved wearable data will be used to evaluate sleep efficiency, total sleep time, sleep consistency, heart rate variability, resting heart rate, and recovery metrics. Baseline and final testing will assess selected reaction and physical performance outcomes. The primary outcome is change in WHOOP-derived sleep efficiency from baseline week to final treatment week.

Participants needed: 150
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: University of California, Los AngelesUpdated: Jun 11, 2026Locations: 1
Eligibility criteria

Age 18 to 35 years. [+6]

Current magnesium supplementation without completion of an appropriate washout b... [+7]

Status: Not yet recruiting

Respiratory Function and Athletic Performance in Professional Soccer Players

This prospective observational study aims to investigate the relationship between respiratory function and multidimensional athletic performance parameters in professional soccer players. The primary hypothesis of the study is that soccer players with enhanced respiratory function and superior respiratory muscle strength will exhibit optimized motor performance outcomes and shorter (faster) reactive reaction times. Investigators will evaluate respiratory muscle strength, spirometric pulmonary functions, dynamic balance, core and abdominal endurance, and reactive visuomotor reaction times during a single testing session within the competitive season.

Participants needed: 31
Trial details
Age: 18-35Biological sex: MaleType: ObservationalSponsor: Istinye UniversityUpdated: Jun 1, 2026
Eligibility criteria

Participants will be actively competing, licensed professional soccer players. -... [+1]

Participants will be excluded if they present with an acute upper or lower respi... [+4]

Status: Recruiting

Comparison of Combined Sprint-Plyometric Training Versus Traditional Strength Training on Speed, Agility, Power, and Movement Quality in Intermediate Rugby Players

Comparison of Combined Sprint-Plyometric Training Versus Traditional Strength Training on Speed, Agility, Power, and Movement Quality in Intermediate Rugby Players: A Randomized Controlled Trial

Participants needed: 64
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: Ibadat International University, IslamabadUpdated: May 18, 2026Locations: 1
Eligibility criteria

Male and female athletes aged 18-25 years [+4]

History of moderate or severe musculoskeletal injuries or surgery within the pas... [+3]

Status: Not yet recruiting

Individualized Training to Improve Aerobic Capacity and 2,000 m Rowing Performance in Youth Rowers

The goal of this randomized clinical trial is to learn whether an individualized rowing training program based on ventilatory thresholds can improve aerobic capacity and 2,000 m rowing performance in youth rowers from Valdivia, Chile. The study will include male and female rowers aged 14 to 18 years who train regularly at Club de Remeros Arturo Prat. The main questions it aims to answer are: Does ventilatory threshold-based individualized training improve maximal oxygen uptake compared with the usual club training program? Does ventilatory threshold-based individualized training improve 2,000 m rowing ergometer performance compared with the usual club training program? Researchers will compare an individualized training group with a usual training group to see if prescribing exercise intensity based on each rower's ventilatory thresholds produces greater improvements in aerobic capacity, rowing performance, and related physiological measures. Participants will: Complete baseline and post-intervention assessments, including a cardiopulmonary exercise test on a rowing ergometer, blood lactate measurements during an incremental rowing test, a 2,000 m rowing ergometer test, body composition assessment, and respiratory muscle strength testing. Be randomly assigned to either an individualized training group or a usual training group. Complete a 12-week rowing training program. Use heart rate monitors during study training sessions so that training intensity, adherence, and safety can be monitored. Report any discomfort, injuries, or adverse events during the study. The individualized training group will train according to heart rate zones derived from each participant's ventilatory thresholds measured at baseline. The usual training group will continue the club's regular training program. The study will also explore individual variability in training response and the proportion of participants who respond or do not respond to each training approach.

Participants needed: 44
Trial details
Age: 14-18Biological sex: AllType: InterventionalSponsor: Universidad San SebastiánUpdated: May 22, 2026Locations: 1
Eligibility criteria

Active membership in Club de Remeros Arturo Prat of Valdivia. [+4]

History of uncontrolled cardiovascular, respiratory, or metabolic disease that c... [+5]